肾功能衰竭患者不同护理干预措施后血液流变学指标的变化

Changes in Hemorheological Parameters in Patients with Renal Failure After Different Nursing Interventions

目的探讨肾功能衰竭患者不同护理干预措施后血液流变学指标的变化及其临床意义。方法选取2021年1月—2022年12月在安阳市第三人民医院血液净化中心接受血液透析治疗的肾功能衰竭患者120例,按照随机数字表法分为对照组和观察组,每组60例。对照组采用常规护理干预措施,观察组在此基础上增加健康教育、心理支持、营养指导和运动干预等综合护理干预措施。比较两组患者治疗前后血液流变学指标(血浆黏度、全血黏度、红细胞压积、红细胞变形指数、红细胞聚集指数)的变化情况,以及生活质量评分和并发症发生率的差异。结果两组患者治疗前各项血液流变学指标均高于正常值,且差异无统计学意义(P>0.05)。治疗后,两组患者各项血液流变学指标均较治疗前降低,且观察组降低幅度大于对照组,差异有统计学意义(P<0.05)。观察组患者的生活质量评分高于对照组,差异有统计学意义(P<0.05)。观察组患者的并发症发生率低于对照组,差异有统计学意义(P<0.05)。结论肾功能衰竭患者采用综合护理干预措施能有效改善血液流变学指标,提高生活质量,降低并发症发生率,值得临床推广应用。

Objective To investigate the changes in hemorheological parameters and their clinical significance in patients with renal failure after different nursing interventions.Methods A total of 120 patients with renal failure who underwent hemodialysis treatment at the Blood Purification Center of Anyang No.3 People's Hospital from January 2021 to December 2022 were selected.They were randomly divided into a control group and an observation group,with 60 cases in each.The control group received routine nursing interventions,while the observation group received comprehensive nursing interventions including health education,psychological support,nutritional guidance,and exercise interventions in addition to routine care.The changes in hemorheological parameters(plasma viscosity,whole blood viscosity,red blood cell hematocrit,red blood cell deformability index,and red blood cell aggregation index)before and after treatment were compared between the two groups,as well as differences in quality of life scores and incidence of complications.Results Before treatment,all hemorheological parameters in both groups were higher than the normal values,with no significant difference between them(P>0.05).After treatment,the hemorheological parameters in both groups decreased compared to before treatment,and the observation group showed a greater reduction than the control group,with significant difference(P<0.05).The quality of life scores in the observation group were higher than those in the control group,with statistical significance(P<0.05).The incidence of complications in the observation group was lower than that in the control group,with statistical significance(P<0.05).Conclusion Comprehensive nursing interventions can effectively improve hemorheological parameters,enhance quality of life,and reduce the incidence of complications in patients with renal failure.These interventions are worth promoting in clinical practice.