继发性甲状旁腺功能亢进症的手术治疗进展

Overview of Surgical Treatment in Patients with Secondary Hyperparathyroidism

继发性甲状旁腺功能亢进症(SHPT)是慢性肾脏病(CKD)较为常见且严重的一种并发症,与CKD患者预后密切相关。目前临床上SHPT多以药物治疗为主。当药物治疗效果较差,甲状旁腺激素(PTH)持续升高且伴有甲状旁腺增生时,患者需采用甲状旁腺切除术(PTX)的治疗。近年来,SHPT的手术治疗,尤其PTX的治疗方式不断发展革新,一定程度上提高了患者的生存质量。为此,本文对目前SHPT患者PTX的治疗进展作一综述,以更好地指导临床治疗。

Secondary hyperparathyroidism(SHPT)is a relatively common and serious complication of chronic kidney disease(CKD),which is closely related to the prognosis of CKD patients.At present SHPT is mainly treated with medication.Due to the less efficient medication therapy parathyroid hormone(PTH)could rise continuously and have risk of the complication to parathy⁃roid hyperplasia,so that parathyroidectomy(PTX)muss be carried out.In recent years the surgical treatment for SHPT,especially PTX,has been continuously developed and revolutionized,which has improved the survival quality of patients to a certain extent.For this reason this article summarizes the current progress of PTX in SHPT patients to give colleagues a better overview of the PTX.