神经质人格对认知重评影响的脑机制

The brain mechanism of neuroticism's influence on cognitive reappraisal

目的:认知重评是个体最常用且最有效的情绪调节策略,它能有效降低个体的负性情绪。而神经质作为一种稳定的与情绪相关的人格特质,被证明与认知重评能力显著负相关,但是为什么高神经质个体的认知重评能力较差目前还不清楚。方法:本研究采用经典的认知重评实验范式,采集较大样本量(n=160)被试的任务态磁共振数据,探讨神经质人格与认知重评之间的脑机制。结果:行为结果发现,在认知重评任务中个体的认知重评能力的得分与神经质人格的得分显著负相关。磁共振的结果发现高神经质得分的个体的内侧前额叶、额下回以及额中回的激活强度减弱,且内侧前额叶、额下回以及额中回的激活强度在神经质人格与认知重评能力的关系中起着部分中介效应。结论:在认知重评任务中,高神经质的个体可能通过影响部分脑区(内侧前额叶、额下回、额中回)的激活水平,进而影响个体的认知重评能力。

Objective:cognitive reappraisal is the most common and effective emotion regulation strategy,which can effectively reduce the negative emotion.Neuroticism,as a stable emotion related personality trait,has been proved to be negatively correlated with cognitive reappraisal ability.However,it is not clear why highly neurotic individuals have poor cognitive reappraisal ability.Methods:using the classic paradigm of cognitive reappraisal,we collected a large sample(n=160)of task state MRI data to ex-plore the brain mechanism between neurotic personality and cognitive reappraisal.Results:In the cognitive reappraisal task,the score of cognitive reappraisal ability was negatively correlated with the score of neu-rotic personality.MRI results showed that the activation intensity of medial prefrontal cortex,inferior frontal gyrus and middle frontal gyrus decreased in individuals with high neuroticism score,and the activa-tion intensity of medial prefrontal cortex,inferior frontal gyrus and middle frontal gyrus played a partial mediating role in the relationship between neuroticism personality and cognitive reappraisal ability.Conclu-sion:In the cognitive reappraisal task,the individuals with high neuroticism may affect the cognitive reap-praisal ability by affecting the activation level of some brain regions(medial prefrontal lobe,inferior frontal gyrus,middle frontal gyrus).