摘要
高良姜素是主要存在于中药高良姜、蜂胶中的一种天然黄酮类化合物。现代研究表明,高良姜素具有抗炎、抗肿瘤、皮肤保护、抗糖尿病及其并发症、抗纤维化、抗病原微生物、神经保护等多种药理活性,应用前景广阔。本文对高良姜素的药理作用及作用机制进行综述,以期为高良姜素在医药领域的开发应用提供理论依据。
Galangin is a natural flavonoid compound mainly existing in Chinese medicinal materials Rhizoma Alpiniae Officinarum and Propolis.Modern studies show that galangin has pharmacological activities such as anti-inflammation,anti-tumor,skin protection,anti-diabetes and its complications,anti-fibrosis,microbial resistance,and neuroprotection,with a broad application prospect.In this paper,the pharmacological activities and mechanism of galangin were summarized,in order to provide a theoretical basis for the development and application of galangin in the field of medicine.
作者
王晓晴
孙允红
赵方舒
尹怡铭
倪雯婷
李保宏
侯林
WANG Xiaoqing;SUN Yunhong;ZHAO Fangshu;YIN Yiming;NI Wenting;LI Baohong;HOU Lin(College of Pharmacy,Shandong University of Traditional Chinese Medicine,Jinan 250355;Qingdao Academy of Chinese Medical Sciences,Shandong University of Traditional Chinese Medicine,Qingdao 266000)
出处
《中药药理与临床》
CAS
CSCD
北大核心
2023年第8期115-120,共6页
Pharmacology and Clinics of Chinese Materia Medica
基金
山东省自然科学基金(编号:ZR2019QH007)
山东省重点研发计划(重大科技创新工程)(编号:2020CXGC010505、2021CXGC010511)
山东省中医药科技项目(编号:2020M009)。
关键词
高良姜素
药理作用
机制
研究进展
Galangin
Pharmacological activities
Mechanism
Research progress