摘要
静止的神经干细胞在受到一定条件的刺激下可以被再激活,重新进入细胞分裂周期,产生新的神经元,为神经系统障碍疾病的细胞治疗带来前景。文中就神经干细胞再激活的外部刺激、内在调控因素以及对神经系统障碍疾病的修复治疗等方面的研究进展进行综述。
The quiescent neural stem cells(NSCs)can be reactivated under the stimulation of certain conditions to re-enter the cell division cycle and generate new neurons,which brings prospects for the cell therapy of nervous system disorders.The research progress on the external stimulation,internal regulatory factors of NSCs reactivation and the repair and treatment of neurological disorders were reviewed.
作者
曾琳
陆彦邑
严博文
高丹丹
何庆华
周邦富
胡鹭
刘媛
ZENG Lin;LU Yan-yi;YAN Bo-wen;GAO Dan-dan;HE Qing-hua;ZHOU Bang-fu;HU Lu;LIU Yuan(Department of Field Medical Equipment,Daping Hospital of Army Medical University,Chongqing 400042,China;Department of Combat Trauma Medicine,Daping Hospital of Army Medical University,Chongqing 400042,China;Department of Special War Wound,Daping Hospital of Army Medical University,Chongqing 400042,China)
出处
《中国临床神经科学》
2023年第4期459-463,475,共6页
Chinese Journal of Clinical Neurosciences
基金
国家自然科学基金课题(编号:81772066)。
关键词
神经干细胞
再激活
神经功能损害
neural stem cell
reactivate
neurological disorders
