肝功能与血脂血清学指标水平检验在脂肪肝中的应用价值分析

Analysis of the Application Value of Liver Function and Blood Lipid Sero⁃logical Index Level Testing in Fatty Liver Disease

目的研究分析肝功能与血脂血清学指标水平检验在脂肪肝中的应用价值。方法选取2020年9月—2022年9月期间南京市溧水区中医院收治的脂肪肝患者80例设为研究组,按照脂肪肝严重程度分为轻度组(n=30)、中度组(n=30)、重度组(n=20),选取同期进行体检的健康者80例设为对照组。对各组受检者的肝功能、血脂血清学指标进行检测与比较,分析肝功能与血脂血清学指标与脂肪肝严重程度的相关性。结果研究组丙氨酸转氨酶水平(67.33±5.82)U/L、天冬氨酸转氨酶水平(66.49±5.88)U/L,高于对照组,差异有统计学意义(t=68.032、68.903,P<0.05)。研究组总胆固醇、三酰甘油水平高于对照组,差异有统计学意义(P<0.05)。重度组、中度组、轻度组丙氨酸转氨酶、天冬氨酸转氨酶、总胆固醇、三酰甘油水平比较,差异有统计学意义(P<0.05)。丙氨酸转氨酶、天冬氨酸转氨酶、总胆固醇、三酰甘油水平与脂肪肝严重程度呈正相关(r=0.91、0.94、0.92、0.90,P<0.05)。结论肝功能与血脂血清学指标水平检验在脂肪肝中的应用价值非常高,可在一定程度上反映患者病情严重程度,为其治疗提供了可靠的指导依据。

Objective To study and analyze the application value of liver function and blood lipid serological index levels in fatty liver disease.Methods 80 patients with fatty liver admitted to the Hospital of Traditional Chinese Medicine in Lishui District,Nanjing from September 2020 to September 2022 were selected as the research group.According to the severity of fatty liver,the patients were divided into mild group(n=30),moderate group(n=30),and severe group(n=20).80 healthy subjects who underwent physical examination during the same period were selected as the control group.The liver function and blood lipid serological indicators of subjects in each group were detected and compared.The correlation between liver function and serum lipid index and the severity of fatty liver was analyzed.Results The levels of alanine aminotransferase(67.33±5.82)U/L and aspartate aminotransferase(66.49±5.88)U/L in the study group were higher than those in the control group,and the difference was statistically significant(t=68.032,68.903,P<0.05).The levels of total cholesterol and triglyceride in the study group were higher than those in the control group,and the difference was statistically significant(P<0.05).There was statistically significant difference in alanine aminotransferase,aspartate aminotransferase,total cholesterol and triglyceride levels among severe group,moderate group and mild group(P<0.05).The levels of alanine aminotransferase,aspartate aminotransferase,total cholesterol and triglyceride were positively correlated with the severity of fatty liver(r=0.91,0.94,0.92,0.90,P<0.05).Conclusion The application value of liver function and blood lipid serological index level testing in fatty liver is very high.It can reflect the severity of the patient's condition to a certain extent and provide reliable guidance for patient treatment.