绒毛膜羊膜炎发病机制及临床管理的研究进展

Research Progress on the Pathogenesis and Clinical Management of Chorioamnionitis

绒毛膜羊膜炎对孕产妇、胎儿和新生儿有深远的影响。近年来,通过及时诊断和治疗,在降低其不良预后方面取得了较大进展。随着对绒毛膜羊膜炎认识的不断深入,临床管理方面也在不断更新。临床绒毛膜羊膜炎一旦诊断,建议尽快分娩,阴道分娩是更安全的选择,产时建议使用抗生素。关于皮质类固醇、硫酸镁的使用,根据诊断时的胎龄不同,治疗方案不同,总体上是有益的。本文针对近年来关于绒毛膜羊膜炎的定义、病因及临床管理方面做一综述。

Chorioamnionitis has profound effects on pregnant women,fetuses and newborns.In recent years,great progress has been made in reducing its poor prognosis through timely diagnosis and treatment.As the understanding of chorioamnionitis continues to deepen,clinical management is also constantly updated.Once clinical chorioamnionitis is diagnosed,it is recommended to give birth as soon as possible.Vaginal delivery is a safer choice,and antibiotics are recommended during delivery.Regarding the use of corticosteroids,magnesium sulfate,treatment options vary according to gestational age at diagnosis,and it is generally beneficial.This article reviews the definition,etiology,and clinical management of chorioamnionitis in recent years.