老年HIV/AIDS患者生活质量及相关因素分析

目的调查杭州市老年HIV/AIDS患者生活质量,分析影响生活质量的相关因素。方法调查2021年2~7月杭州市西溪医院治疗的≥60岁的HIV/AIDS患者。以问卷调查的形式收集患者人口学资料、HIV/AIDS相关资料和生活质量等。生活质量采用MOSHIV量表和SF-36量表。通过相关性分析和多元线性回归分析生活质量的相关因素。结果共调查245例老年HIV/AIDS患者。MOSHIV量表生理总分和心理总分分别为(52.1±7.1)分和(52.7±5.9)分;SF-36量表生理总分和心理总分分别为(51.6±6.8)分和(48.1±6.5)分。相关性分析结果显示,年龄与患者MOSHIV量表生理总分(P<0.001)和SF-36量表生理总分(P=0.001)呈负相关;BMI、家庭人均月收入与MOSHIV量表生理和心理总分成正相关(P<0.05)。结论老年HIV/AIDS患者年龄增加与生理健康下降相关;患者营养和经济状况则与患者生理和心理相关生活质量呈正相关。

Objective To investigate the quality of life(QoL)among old patients with human immunodeficiency virus(HIV)/acquired immunodeficiency syndrome(AIDS),and to analyze the related factors influencing QoL.Methods This cross-sectional study enrolled≥60 years patients with HIV/AIDS treated at Affiliated Hangzhou Xixi Hospital,Zhejiang University School of Medicine from April 2021 to July 2021.The demographics,disease and QoL information were collected by questionnaires.QoL was assessed by HIV-targeted Medical Outcomes Study HIV Health Survey(MOSHIV)and 36-Item Short Form Survey(SF-36).The correlated factors of QoL was analyzed using correlation analysis and multiple linear regression.Results A total of 245 old patients with HIV/AIDS were investigated.The total physical and psychological scores of the MOSHIV scale were 52.1±7.1 and 52.7±5.9,respectively;the total physical and psychological scores of the SF-36 scale were 51.6±6.8 and 48.1±6.5,respectively.The results of correlation analysis showed that age was negatively correlated with physical score of MOSHIV scale(P<0.001)and SF-36 scale score(P=0.001).Meanwhile,body mass index and family monthly income was positively correlated with the total physical and psychological scores of MOSHIV scale(P<0.05).Conclusion Increasing age in old patients with HIV/AIDS is correlated with a decline in physical health;nutrition and economic status are positively correlated with physical and psychological related QoL in old patients with HIV/AIDS.