针刺泻法治疗痰热壅肺型慢性阻塞性肺疾病急性加重临床观察

Twirling-reducing Needling Manipulation Method in the Treatment of Acute Exacerbation Chronic Obstructive Pulmonary Disease of Phlegm-heat Obstructing Lung Type

目的观察针刺泻法治疗痰热壅肺型慢性阻塞性肺疾病急性加重(AECOPD)患者的临床疗效。方法选取2020年10月—2021年10月江西省中西医结合医院呼吸科收治的痰热壅肺型AECOPD患者60例,随机分为对照组(30例)、试验组(30例)。2组均给予慢性阻塞性肺疾病的综合治疗,试验组在此基础上加用针刺泻法治疗,连续2周,隔日1次。比较2组患者的肺功能指标、6 min步行距离(6MWD)、炎症指标[血清白细胞介素-1β(IL-1β)、白细胞介素-6(IL-6)、超敏C反应蛋白(hs-CRP)、血清淀粉样蛋白A(SAA)]及不良反应发生情况。结果与治疗前相比,治疗后2组的肺功能及6MWD有所提升,炎症指标有所下降(P<0.05)。与对照组相比,试验组肺功能、6MWD改善明显,炎症因子(IL-1β、IL-6、hs-CRP、SAA)下降明显(P<0.05)。结论对于痰热壅肺型AECOPD患者,针刺泻法可改善患者的气道炎症和肺功能、可有效预防气道重塑,对于AECOPD的临床治疗具有参考意义。

Objective To observe the clinical effect of twirling-reducing needling manipulation method in the treatment of acute exacer⁃bation chronic obstructive pulmonary disease(AECOPD)of phlegm-heat obstructing lung type.Methods 60 cases of AECOPD patients with phlegm heat obstructing lung type admitted to Jiangxi Provincial Hospital of Integrated Traditional and Western Medicine from Oc⁃tober 2020 to October 2021 were selected and randomly divided into control group(30 cases)and experimental group(30 cases).Both groups were given comprehensive treatment of chronic obstructive pulmonary disease,and the experimental group was additionally twirling-reducing needling manipulation method for 2 consecutive weeks,once every other day.The pulmonary function indexes,6-min walking distance(6MWD),inflammatory indexes(serum interleukin-1β(IL-1β),interleukin-6(IL-6),hypersensitive C-reactive protein(hs-CRP),serum amyloid A(SAA))and the occurrence of adverse reactions were compared between the two groups.Results Compared with before treatment,the lung function and 6MWD of the 2 groups were improved after treatment,and the inflammatory in⁃dexes were decreased(P<0.05).Compared with the control group,lung function and 6MWD in experimental group were significantly im⁃proved,and inflammatory factors(IL-1β,IL-6,hs-CRP,SAA)were significantly decreased(P<0.05).Conclusion For AECOPD pa⁃tients with phlegm-heat obstructing lung type,twirling-reducing needling manipulation method can improve airway inflammation and lung function and effectively prevent airway remodeling,which is of reference significance for the clinical treatment of AECOPD.