摘要
Dear Editor,Cells enter senescence,or irreversible growth arrest,when exposed to stressors such as DNA damage,epigenetic alterations and chronic inflammation(Zhao and Chen,2022).In aging and aging-related diseases,senescent cells are known to accumulate across tissues and organs(Sun et al.,2022;Lopez-Otin et al.,2023).
基金
supported by the National Key Research and Development Program of China (2020YFA0804000)
the Strategic Priority Research Program of the Chinese Academy of Sciences (XDA16000000)
the National Natural Science Foundation of China (81921006,82125011,92149301,92168201,91949209,92049304,92049116,32121001,82271600,82192863,32000500,82122024,82071588,32000510)
the National Key Research and Development Program of China (2018YFC2000100,2018YFA0107203,2020YFA0112200,2021YFF1201005,the STI2030-Major Projects-2021ZD0202400,2022YFA1103700)
CAS Project for Young Scientists in Basic Research (YSBR-076,YSBR-012)
the Program of the Beijing Natural Science Foundation (Z190019)
K.C.Wong Education Foundation (GJTD-2019-06,GJTD-2019-08)
The Pilot Project for Public Welfare Development and Reform of Beijingaffiliated Medical Research Institutes (11000022T000000461062)
Youth Innovation Promotion Association of CAS (E1CAzW0401,2022083)
Young Elite Scientists Sponsorship Program by CAST (YESS20200012,YESS20210002)
the Informatization Plan of Chinese Academy of Sciences (CAS-WX2021SF-0301,CASWX2022SDC-XK14,CAS-WX2021SF-0101)
the Tencent Foundation (2021-1045).
