胃潴留量对心肺复苏后神经功能的影响

Effect of gastric retention on neurological function after cardiopulmonary resuscitation

目的探讨胃潴留量对心肺复苏(CPR)后神经功能的影响。方法发生心脏骤停行CPR成功的患者450例,出院时对患者进行格拉斯哥-匹兹堡脑功能表现(CPC)评分,根据CPC评分将患者分为神经功能良好组(CPC评分≤2分,218例)和神经功能不良组(CPC评分≥3分,232例)。比较两组患者年龄、CPR时长以及CPR后24 h胃潴留量、pH值和乳酸水平,采用多因素logistic分析CPR后患者神经功能不良的危险因素。结果神经功能不良组年龄较大,CPR时长较长,CPR后24 h胃潴留量较多,pH值较低,乳酸水平较高(P<0.05)。CPR时长较长和CPR后24 h胃潴留量较多是CPR后患者神经功能不良的独立危险因素(P<0.05)。结论CPR后24 h胃潴留量较多是心脏骤停患者CPR后神经功能不良的独立危险因素。

Objective To explore the effect of gastric retention on neurological function after cardiopulmonary resuscitation(CPR).Methods A total of 450 patients underwent CPR successfully after cardiac arrest were assessed by Glasgow-Pittsburgh cerebral functional performance(CPC)score at discharge.The patients were divided into two groups of A(CPC score≤2 points,218 cases)and B(CPC score≥3 points,232 cases).The age,duration of CPR,gastric retention,pH and lactic acid(Lac)24 hours after CPR were compared between the two groups.The risk factors for neurological dysfunction in the patients after CPR were analyzed by multivariate logistic analysis.ResultsCompared with group A,the age was older,duration of CPR was longer,gastric retention was more,pH value was lower and Lac was higher in group B 24 hours after CPR(P<0.05).The longer duration of CPR and higher gastric retention 24 hours after CPR were the independent risk factors for neurological dysfunction of the patients after CPR(P<0.05).Conclusion Higher gastric retention 24 hours after CPR is an independent risk factor for neurological dysfunction in the patients after CPR.