贝母瓜蒌散离子导入联合左氧氟沙星治疗社区获得性肺炎的临床疗效

The effect of Fritillaria Gualou powder iontophoresis combined with Levofloxacin in the treatment of community acquired pneumonia

目的观察贝母瓜蒌散离子导入联合左氧氟沙星治疗社区获得性肺炎(community acquired pneumonia,CAP)的临床疗效。方法70例CAP患者随机分为试验组和对照组。对照组给予注射用左氧氟沙星0.5 g静脉滴注,每天1次;试验组在对照组的基础上加用贝母瓜蒌散离子导入治疗,每天1次,每次治疗时间20 min,1次2贴,两组疗程均为7 d。结果试验组总有效率(94.74%)高于对照组(75.01%),差异具有统计学意义(P<0.05);住院时间试验组[(6.2±0.8)d]明显短于对照组[(7.9±1.1)d],差异具有统计学意义(P<0.05),两组不良反应的差异则无统计学意义。结论贝母瓜蒌离子导入给药可提高左氧氟沙星治疗CAP的临床疗效,为中西医结合治疗CAP提供了新的治疗策略。

Objective To study the clinical efficacy of Fritillaria Gualou powder iontophoresis combined with Levofloxacin in the treatment of community acquired pneumonia.Methods 70 patients with community-acquired pneumonia were randomly divided intoexperimental group and control group.The control group was given the treatment of levofloxacin 0.5 g injection intravenously once a day,while the experimental group were given the treatment of Fritillaria Gualou powder iontophoresis on the basis of the control group,once a day,20 minutes.Each time,2 patches each time,and the course of treatment in both groups was 7 days.Results The total effective rate of the experimental group was significantly higher than the control group(94.74%vs 75.01%,P<0.05),and the hospital stay was significantly shorter than the control group[(6.2±0.8)d vs(7.9±1.1)d,P<0.05].There was no significant difference in adverse reactions between the two groups.Conclusion Fritillaria Gualou powder iontophoresis can improve the clinical efficacy of levofloxacin in the treatment of CAP,and provide a new treatment strategy for the treatment of CAP with integrated traditional chinese and western medicine.