西北地区老年AMI患者电子健康素养量表评分与MACE的相关性

Correlation between e-health literacy scale score and MACE in aged AMI patients in northwest China

目的:分析西北地区老年急性心肌梗死(AMI)患者电子健康素养量表评分与主要不良心血管事件(MACE)的相关性。方法:依据是否发生MACE,于我院治疗的529例患者被分为MACE组(212例)与无MACE组(317例)。分析AMI患者电子健康素养量表(eHEALS)评分与MACE的相关性,AMI患者发生MACE的影响因素及其对MACE的预测价值。结果:529例AMI患者中MACE发生率为40.08%。与无MACE组比较,MACE组年龄、高血压、纽约心脏协会(NYHA)分级≥Ⅲ级、糖尿病、恐惧运动、eHEALS评分<32分比例,总胆固醇(TC)水平均显著升高(P<0.05或<0.01)。Spearman相关性分析显示,eHEALS评分与MACE发生情况呈显著正相关(r=0.203,P=0.001)。多因素Logistic回归分析显示,年龄、NYHA分级≥Ⅲ级、TC、糖尿病、恐惧运动、eHEALS评分<32分是AMI患者发生MACE的独立危险因素(OR=1.149~2.399,P<0.05或<0.01)。ROC曲线显示,上述六项指标联合检测预测AMI患者发生MACE的曲线下面积为0.725,显著高于各项单独检测,P均=0.001;灵敏度为73.1%,特异度为59.9%。结论:西北地区老年急性心肌梗死患者电子健康素养量表评分与MACE显著相关性。

Objective:To analyze correlation between e-health literacy scale score and major adverse cardiovascular events(MACE)in aged patients with acute myocardial infarction(AMI)in northwest China.Methods:According to occurrence of MACE,a total of 529 AMI patients treated in our hospital were divided into MACE group(n=212)and no MACE group(n=317).Correlation between the e-health literacy scale(eHEALS)score and MACE,influencing factors of MACE in AMI patients and their predictive value for MACE were analyzed.Results:Incidence rate of MACE in 529 AMI patients was 40.08%.Compared with no MACE group,there were significant rise in age,percentages of hypertension,NYHA class≥Ⅲ,diabetes mellitus(DM),fear of exercise and eHEALS<32 scores and level of total cholesterol(TC)in MACE group(P<0.05 or<0.01).Spearman correlation analysis indicated that eHEALS score was significant positively correlated with incidence of MACE(r=0.203,P=0.001).Multivariate Logistic regression analysis indicated that age,NYHA class≥Ⅲ,TC,DM,fear of exercise and eHEALS<32 scores were independent risk factors for MACE in AMI patients(OR=1.149~2.399,P<0.05 or<0.01).ROC curve indicated that AUC of combined detection of above six indexes predicting MACE in AMI patients was 0.725,which was significantly higher than each single detection,P=0.001 all;sensitivity was 73.1%and specificity was 59.9%.Conclusion:E-health literacy scale score is significantly correlated with MACE in aged patients with acute myocardial infarction from northwest China.