宫腔镜下息肉切除术联合曼月乐放置对患者术后子宫内膜厚度和性激素水平影响分析

Effect of hysteroscopic polyp resection combined with Mirena placement on endometrial thickness and sex hormone levels

目的研究宫腔镜电切术联合曼月乐环对子宫内膜息肉患者内膜厚度和性激素水平的影响,为子宫内膜息肉的治疗提供多种方案。方法收集2019年1月—2022年1月接受宫腔镜下子宫内膜息肉切除术的患者70例。根据随机数字表法分为对照组与观察组各35例。对照组使用宫腔镜电切术联合术后口服黄体酮胶囊治疗,观察组使用宫腔镜电切术联合曼月乐环治疗,比较两组治疗前后子宫内膜厚度、月经量、性激素水平、并发症发生率和复发率。结果术后3、6、12个月观察组子宫内膜厚度和月经量明显低于对照组,差异具有统计学意义(P<0.05);观察组术后3个月性激素水平优于对照组,差异具有统计学意义(P<0.05)。观察组术后12个月并发症发生率及复发率低于对照组,差异具有统计学意义(P<0.05)。结论宫腔镜下电切术联合曼月乐治疗子宫内膜息肉患者能够降低子宫内膜厚度,减少月经量,改善性激素水平,降低并发症发生率和复发风险。

Objective To explore of the effect of hysteroscopic electrodesiccation combined with Mirena ring on endometrial thickness and sex hormone levels,and to provide multiple options for the treatment of endometrial polyps.Methods A total of 70 patients with endometrial polyps treated in our hospital from January 2019 to January 2022 were enrolled and randomly divided into a control group and an observation group,with 35 patients in each group.The control group was treated with hysteroscopic electrosurgery combined with post-operative oral progesterone capsules,while the observation group was treated with hysteroscopic electrosurgery combined with the Mirena ring.The endometrial thickness,menstrual fluid volume,sex hormone levels,complication rate,and recurrence rate were compared between the two groups before and after treatment.Results The endometrial thickness and menstrual fluid volume of the observation group were significantly lower than those of the control group at the 3rd,6th,and 12th months after surgery(P<0.05);the sex hormone level of the observation group was better than that of the control group at the 3rd month after surgery(P<0.05);the complication rate and recurrence rate of the observation group were lower than those of the control group at the 12-month follow-up visit(P<0.05).Conclusion Hysteroscopic electrosurgical resection combined with Mirena is effective in reducing endometrial thickness and menstrual volume,improving sexual hormone levels,and reducing complications and recurrence risk.