定喘汤治疗痰热蕴肺型肺部感染临床观察

Dingchuan Decoction in the Treatment of Pulmonary Infection with Phlegm Heat Accumulation in Lung Type

目的探讨定喘汤在痰热蕴肺型肺部感染患者中的临床效果及药物安全性。方法选取2019年10月—2021年10月肺部感染患者70例为研究对象,按随机数字表法分为对照组和观察组,各35例。对照组采取常规西医治疗,观察组在对照组基础上联合定喘汤治疗,10 d后评估比较2组的炎症指标水平、治疗效果、安全性。结果治疗后,观察组的白细胞(WBC)计数和C反应蛋白(CRP)水平比对照组低(P<0.05);观察组的总有效率97.14%(34/35)高于对照组的82.86%(29/35)(P<0.05);观察组治疗后不良反应发生率5.71%(2/35)低于对照组的14.29%(5/35),安全性高于对照组(P>0.05)。结论在西医治疗基础上联合定喘汤能提高痰热蕴肺型肺部感染患者的治疗效果,能降低WBC和CRP水平,且未增加药物不良反应发生率,有一定推广价值。

Objective To investigate the clinical effect and drug safety of Dingchuan decoction in patients with pulmonary infection with phlegm-heat accumulation in lung type.Methods A total of 70 patients with pulmonary infection from October 2019 to October 2021 were selected and divided into two groups by random number table method,with 35 cases in each group.The control group was treated with conventional Western medicine,while the observation group was treated with Dingchuan decoction.After 10 days of treat-ment,the effect of patients was evaluated,and the therapeutic effect and safety were compared between the two groups.Results After treatment,the white blood cell(WBC)count and C-reactive protein(CRP)level in observation group were lower than those in control group(P<0.05).The total effective rate of observation group was 97.14%(34/35),which was higher than that of control group(82.86%,29/35)(P<0.05).The incidence of adverse reactions after treatment in the observation group was 5.71%(2/35),which was lower than that in the control group(14.29%,5/35),and the safety was higher than that in the control group(P>0.05).Conclusion On the basis of Western medicine,Dingchuan decoction can improve the therapeutic effect,reduce the levels of WBC and CRP,and does not increase the incidence of adverse drug reactions,which has certain promotion value.