老年夜间高血压发生机制的中西医研究进展

Research Progress of Traditional Chinese and Western Medicine on the Mechanism of Senile Nocturnal Hypertension

夜间高血压作为高血压病靶器官损害和心血管事件的独立危险因素,逐渐得到国内外学者的重视。从现代医学的角度来看,高血压病的发病机制并不明确,自主神经系统功能异常、肾素-血管紧张素-醛固酮系统活性改变及盐敏感和盐摄入量过高等是老年夜间高血压重要发病机制。相对而言,中医学具有明确的病因病机特点,中医独特的理论体系、辨证论治的特点,造就了老年夜间高血压中医病机相对明确的特性,经探究,发现情志因素、饮食劳逸、体质禀赋等是其主要病理机制。

Nocturnal hypertension is an independent risk factor for hypertensive target organ damage and cardiovascular events.From the perspective of modern medicine,the pathogenesis of hypertension is not clear,abnormal autonomic nervous system function,in-creased activity of the renin-angiotensin-aldosterone system,salt sensitivity and high salt intake are important factors for nighttime hy-pertension in the elderly.Relatively speaking,traditional Chinese medicine has clear etiological and pathogenesis characteristics.The unique theoretical system of traditional Chinese medicine and the characteristics of syndrome differentiation and treatment have cre-ated relatively clear characteristics of the pathogenesis of nocturnal hypertension in the elderly.After investigation,it is found that emotional factors,diet,work and rest,and physical endowment are the main pathological mechanisms.