摘要
目的探讨无创呼吸机治疗老年慢性阻塞性肺疾病急性加重(AECOPD)合并呼吸衰竭患者的临床疗效。方法选取2018年6月至2020年6月本院收治的120例老年AECOPD合并呼吸衰竭患者作为研究对象,按照随机抽签法分为对照组与观察组,每组60例。两组均行内科常规治疗,对照组在常规治疗基础上联合经鼻导管持续低流量吸氧治疗,观察组在常规性治疗基础上联合无创呼吸机治疗,比较两组临床疗效及治疗前后血气指标[pH值、动脉血氧分压(PaO_(2))、动脉血二氧化碳分压(PaCO_(2))]、心率和呼吸频率。结果观察组治疗总有效率(98.33%)高于对照组(86.67%),差异有统计学意义(P<0.05)。治疗后,观察组pH值(7.45±0.18)、PaO_(2)水平[(78.66±5.52)mmHg(1 mmHg=0.133 kPa)]均高于对照组[(7.21±0.25)、(70.25±5.25)mmHg],PaCO_(2)水平[(40.36±5.25)mmHg]低于对照组[(58.69±5.24)mmHg],差异有统计学意义(P<0.05)。治疗后,观察组呼吸频率[(22.51±3.69)次/min]、心率[(92.36±5.15)次/min]均慢于对照组[(29.22±3.54)、(102.25±5.36)次/min],差异有统计学意义(P<0.05)。结论无创呼吸机治疗AECOPD合并呼吸衰竭效果显著,能改善患者动脉血气指标,稳定其心率及呼吸频率。
Objective To explore the clinical efficacy of non-invasive ventilator in the treatment of elderly patients with acute exacerbation of chronic obstructive pulmonary disease(AECOPD)with respiratory failure.Methods 120 elderly AECOPD patients with respiratory failure admitted to our hospital from June 2018 to June 2020 were selected as the research subjects,and they were divided into the control group and the observation group according to the random drawing method,with 60 cases in each group.Both groups received routine medical treatment,the control group combined with continuous low flow oxygen inhalation through nasal catheter on the basis of routine treatment,and the observation group was combined with noninvasive ventilator on the basis of routine treatment,the clinical efficacy and blood gas indicators[pH value,arterial oxygen partial pressure(PaO_(2)),arterial carbon dioxide partial pressure(PaCO_(2))]before and after treatment,heart rate,and respiratory rate were compared between two groups.Results The total effective rate in the observation group(98.33%)was higher than that in the control group(86.67%),with a statistically sig-nificant difference(P<0.05).After treatment,the pH value(7.45±0.18),PaO_(2) level([78.66±5.52]mmHg[1 mmHg=0.133 kPa]),in the observation group were higher than those in the control group([7.21±0.25],[70.25±5.25]mmHg),and PaCO_(2) level([40.36±5.25]mmHg)in the observation group was lower than that in the control group([58.69±5.24]mmHg),and the differences were statistically significant(P<0.05).After treatment,the respiratory rate([22.51±3.69]beats/min)and heart rate([92.36±5.15]beats/min)in the observation group were lower than those in the control group([29.22±3.54],[102.25±5.36]beats/min),and the differences were statistically significant(P<0.05).Conclusion Non-invasive ventilator has significant effect in the treatment of AECOPD with respiratory failure,which can improve the arterial blood gas index of patients and stabilize their heart rate and respiratory rate.
作者
张云
ZHANG Yun(Department of Respiratory and Critical Care Medicine,General Hospital of Northern Theater Command,Shenyang,Liaoning,110000,China)
出处
《当代医学》
2023年第20期106-109,共4页
Contemporary Medicine
基金
辽宁省自然科学基金(2019-ZD-0964)。
关键词
无创呼吸机
老年患者
慢性阻塞性肺疾病急性加重
呼吸衰竭
动脉血气
Non-invasive ventilator
Elderly patients
Acute exacerbation of chronic obstructive pulmonary disease
Respiratory failure
Arterial blood gas