康柏西普联合激光治疗视网膜静脉血管阻塞并发黄斑囊样水肿的临床效果

Clinical effect of conbercept combined with laser in the treatment of retinal vein vascular occlusion complicated with cystoid macular edema

目的探讨康柏西普结合激光治疗视网膜静脉血管阻塞并发黄斑囊样水肿的临床效果。方法选取2019年12月至2021年5月本院收治的66例视网膜静脉血管阻塞并发黄斑囊样水肿患者作为研究对象,依据随机数字表法分为单一组与联合组,每组33例。单一组采用激光治疗,联合组在单一组基础上采用康柏西普治疗,比较两组临床疗效、黄斑中心凹厚度(CMT)、最佳矫正视力(BCVA)及并发症发生率。结果联合组治疗总有效率为100.00%,高于单一组的69.70%,差异有统计学意义(P<0.05);治疗后,联合组CMT薄于单一组,BCVA高于单一组,差异有统计学意义(P<0.05);联合组并发症发生率为6.06%,单一组为18.18%,两组比较差异无统计学意义。结论康柏西普联合激光治疗视网膜静脉血管阻塞并发黄斑囊样水肿疗效显著,可改善患者CMT、BCVA,降低并发症发生率,值得临床推广应用。

Objective To investigate the clinical effect of conbercept combined with laser in the treatment of retinal vein vascular occlusion com-plicated with cystoid macular edema.Methods 66 patients with retinal vein vascular occlusion complicated with macular cystoid edema admitted to our hospital from December 2019 to May 2021 were selected as the study subjects,and were divided into the single group and the combined group according to the random number table method,with 33 cases in each group.The single group received laser treatment,while the combined group re-ceived concomitant therapy on the basis of the single group,the clinical efficacy,macular fovea thickness(CMT),best visual acuity correction(BC-VA)and incidence of complications between the two groups were compared.Results The total effective rate in the combined group was 100.00%,which was higher than 69.70%in the single group,the difference was statistically significant(P<0.05);after treatment,the CMT in the combined group was thinner than that in the single group,and the BCVA was higher than that in the single group,the differences were statistically significant(P<0.05).The incidence of complications in the combined group was 6.06%,while in the single group was 18.18%,there was no statistically signifi-cant difference between the two groups.Conclusion Conbercept combined with laser in the treatment of retinal vein vascular occlusion complicated with macular cystoid edema has significant effect,which can improve CMT and BCVA,reduce the incidence of complications,and is worthy of clini-cal promotion and application.