砭贴疗法对老年人身心状态调适效应的双盲随机对照试验

Double blind randomized controlled trial on the effect of Biantie therapy on the adjustment of the elderly's physical and mental states

目的:观察砭贴疗法对老年人身心状态调适的效果。方法:于2022年9月20日—10月10日收集的60例受试者随机分为砭贴组和安慰贴组,每组30例。干预14 d后比较2组干预前后PSQI评分、SAS评分及SDS评分及血清5-羟色胺(5-HT)水平、多巴胺(DA)水平的变化情况,并记录试验过程中的不良反应。结果:两组受试者经干预后PSQI评分显著下降(P<0.01),砭贴组优于安慰贴组(P<0.05)。其中在睡眠时间和睡眠效率评分方面,砭贴组经干预显著下降(P<0.01),且在睡眠效率评分方面,砭贴组优于安慰贴组(P<0.05),砭贴组评分下降更明显。两组受试者经干预后SAS评分显著下降(P<0.01)。其中在惊恐、心慌、晕厥感、尿意频繁、噩梦评分方面,砭贴组干预后出现不同程度下降(P<0.05,P<0.01)。两组经干预后SDS评分显著下降(P<0.01),其中在心悸评分方面,砭贴组经干预后显著下降(P<0.05)。两组经干预后血清5-HT、DA水平显著下降(P<0.01)。两组不良反应发生率无明显差异。结论:砭贴疗法可调适老年人失眠、焦虑、抑郁等身心状态,且安全性良好。

Objective:To observe the effect of Biantie therapy on the adjustment of the elderly's physical and mental states.Methods:A total of 60 subjects collected from September 20 to October 10,2022 were randomly divided into Biantie group and Consolation control Tie group,30 in each group.After 14 days of intervention,PSQI score,SAS score,SDS score and the changes of serum 5-hydroxytryptamine(5-HT)and dopamine(DA)levels between the two groups before and after intervention were compared,and the adverse reactions during the trial were recorder.Results:After intervention,the PSQI scores of the two groups of subjects were significantly reduced(P<0.01),and the score of the Biantie group decreased more significantly(P<0.05).In terms of sleep time and sleep efficiency scores,the Biantie group showed a significant decrease after intervention(P<0.01),and in terms of sleep efficiency scores,there was a statistically significant difference between the groups before and after intervention(P<0.05),with the Biantie group showing a more significant decrease in scores.After intervention,the SAS scores of the two groups of subjects significantly decreased(P<0.01).In terms of panic,palpitation,syncope,frequent urination and nightmares,the Biantie group showed varying degrees of decrease after intervention(P<0.05,P<0.01).After intervention,the SDS score of the two groups significantly decreased(P<0.01),and in terms of palpitations score,the Biantie group significantly decreased(P<0.05).After intervention,the levels of serum 5-HT and DA in both groups significantly decreased(P<0.01).There was no significant difference in the incidence of adverse reactions between the two groups.Conclusion:Biantie therapy can adjust the physical and mental state of the elderly people such as insomnia,anxiety,and depression,and has good safety.