摘要
目的 探讨中药注射剂的抗肿瘤作用机制。方法 检索中国知网(CNKI)、维普(VIP)、万方(WanFang)及PubMed,The Cochrane Library,ScienceDirect等数据库中有关中药注射剂抗肿瘤作用的实验研究文献,检索时限为2010年1月1日至2022年12月31日,总结中药注射剂的抗肿瘤作用机制。结果 中药注射剂通过抑制肿瘤细胞的增殖、侵袭和迁移,诱导肿瘤细胞凋亡,抑制肿瘤血管生成,调节机体免疫,逆转肿瘤细胞耐药等机制实现抗肿瘤作用。结论 中药注射剂能通过多途径发挥抗肿瘤作用。
Objective To investigate the anti-tumor mechanisms of traditional Chinese medicine(TCM)injections.Methods The experimental research literature related to the anti-tumor effects of TCM injections was searched from databases such as CNKI,VIP,WanFang,PubMed,The Cochrane Library,and ScienceDirect from January 1,2010 to December 31,2022.The anti-tumor mechanisms of TCM injections were summarized.Results TCM injections achieved anti-tumor effects by inhibiting the proliferation,invasion,and migration of tumor cells,inducing tumor cell apoptosis,inhibiting tumor angiogenesis,regulating the body's immune system,and reversing the resistance of tumor cells.Conclusion TCM injections can exert anti-tumor effects through multiple pathways.
作者
肖霄
周阳云
陈君君
韩永龙
XIAO Xiao;ZHOU Yangyun;CHEN Junjun;HAN Yonglong(Shanghai University of Traditional Chinese Medicine,Shanghai,China 200437;Shanghai University of Medicine&Health Sciences,Shanghai,China 201318;Shanghai Sixth People's Hospital Affiliated to Shanghai Jiao Tong University School of Medicine,Shanghai,China 200233)
出处
《中国药业》
CAS
2023年第19期151-154,I0001,共5页
China Pharmaceuticals
基金
国家自然科学基金青年科学基金项目[82003987]
上海市科技计划项目[20ZR1442400]
上海市浦东新区卫生健康委员会卫生计生科研项目[PW2021E-03]。
关键词
中药注射剂
抗肿瘤
作用机制
traditional Chinese medicine injection
anti-tumor effect
mechanism
