急性中耳炎患儿血清降钙素原检测的价值

The value of serum procalcitonin detection in children with acute otitis media

目的探讨急性中耳炎(AOM)患儿血清降钙素原(PCT)检测的价值。方法回顾性选取本院2020年1月——2022年1月接诊的46例AOM患儿为观察对象,将其纳入观察组[其中23例予以常规治疗,23例予以PCT指导治疗],另选取同期于本院体检的46例健康儿童,纳入参考组。两组均检测血清PCT、C反应蛋白(CRP)、白细胞计数(WBC),对比两组检测结果;对比患儿治疗后的PCT、CRP、WBC检测结果。结果观察组PCT、CRP、WBC水平均较参考组高,差异有统计学意义(P<0.05)。PCT指导治疗组的PCT、CRP、WBC水平均较常规治疗组低,差异有统计学意义(P<0.05)。结论PCT、CRP、WBC检测均可为AOM提供诊断依据,而根据PCT检测结果指导治疗可显著缓解患儿病情。

Objective To investigate the value of serum procalcitonin(PCT)in children with acute otitis media(AOM).Methods A total of 46 children with AOM who were admitted to our hospital from January 2020 to January 2022 were retrospectively selected as observation objects and included in the observation group(23 cases were given routine treatment,23 cases were given PCT-guided treatment).Forty-six healthy children who underwent physical examination in our hospital during the same period were selected and included in the reference group.Serum PCT,C-reactive protein(CRP),and white blood cell count(WBC)were detected in both groups,and the detection results of the two groups were compared;the detection results of PCT,CRP,and WBC in the children after treatment were compared.Results The levels of PCT,CRP and WBC in the observation group were higher than those in the reference group,and the difference was statistically significant(P<0.05).The levels of PCT,CRP and WBC in the PCT-guided treatment group were lower than those in the conventional treatment group,and the difference was statistically significant(P<0.05).Conclusion The detection of PCT,CRP and WBC can provide the basis for the diagnosis of AOM,and the guidance of treatment based on the results of PCT detection can significantly alleviate the condition of children.