摘要
大部分痛风患者可通过一线药物治疗实现无发作,但仍有部分患者治疗无效而发展为难治性痛风(RG)。其引起的关节破坏和功能损害严重影响患者的生活质量和寿命,给家庭和社会造成重大负担。难治性痛风的治疗尚缺少统一的专家共识,本文对难治性痛风急性期药物治疗、降尿酸药物治疗和手术治疗的相关进展进行综述,以期为临床上难治性痛风的治疗提供支持。
Most patients with gout achieve total relief by conventional therapy,but there are still some who do not respond well and develop into refractory gout(RG).RG causes joint destruction and functional impairment,seriously impairs the quality of life and imposes a substantial burden to families.So far,there is no unified consensus formed for RG.This review is aimed to introduce several therapeutic approaches for RG,including drug and surgical therapy.
作者
柏李裕年
焦洋
BAI Li-yu-nian;JIAO Yang(Department of General Practice(General Internal Medicine),Peking Union Medical College Hospital,Chinese Academy of Medical Sciences&Peking Union Medical College,Beijing 100730,China)
出处
《中华临床免疫和变态反应杂志》
CAS
2023年第4期357-361,共5页
Chinese Journal of Allergy & Clinical Immunology
基金
中央高水平医院临床科研专项(2022-PUMCH-A-017及2022-PUMCH-B-045)。
