血塞通联合西药治疗冠心病患者的临床疗效观察

Observation on the Clinical Efficacy of Xuesaitong Combined with Western Medicine in the Treatment of Patients with Coronary Heart Disease

目的:分析血塞通联合西药治疗冠心病的效果。方法:选取2021年11月—2023年4月青海省心脑血管病专科医院诊治的冠心病患者64例作为观察对象,根据随机数字表法分为对照组与观察组,各32例。对照组给予常规治疗,观察组在常规治疗基础上给予血塞通治疗。比较两组患者临床疗效、血液流变学指标、心功能指标、不良反应发生情况。结果:观察组治疗总有效率高于对照组,差异有统计学意义(P=0.045);治疗后,观察组全血高切黏度、全血低切黏度、全血还原黏度、血浆黏度均低于对照组,差异有统计学意义(P<0.001);治疗后,观察组左室射血分数高于对照组,左心室舒张末期直径、左室收缩末期容积低于对照组,差异有统计学意义(P<0.001);观察组不良反应发生率低于对照组,差异有统计学意义(P=0.039)。结论:血塞通治疗冠心病效果显著,能够优化血液流变学指标,促进心功能恢复,减少不良反应。

Objective:To analyze the effect of Xuesaitong combined with western medicine in the treatment of coronary heart disease.Methods:64 patients with coronary heart disease diagnosed and treated in Qinghai Provincial Cardiovascular and Cerebrovascular Hospital from November 2021 to April 2023 were selected as the observation subjects.According to the random number table method,they were divided into a control group and an observation group,with 32 cases in each group.The control group was given conventional treatment,and the observation group was given Xuesaitong treatment on the basis of conventional treatment.The clinical efficacy,hemorrheological indicators,cardiac function indicators,and occurrence of adverse reactions were compared between the two groups of patients.Results:The total effective rate of treatment in the observation group was higher than that in the control group,and the difference was statistically significant(P=0.045);After treatment,the whole blood high-shear viscosity,whole blood low-shear viscosity,whole blood reduced viscosity,and plasma viscosity of the observation group were all lower than those of the control group,and the differences were statistically significant(P<0.001);After treatment,the left ventricular ejection fraction of the observation group was higher than that of the control group,and the left ventricular end-diastolic diameter and left ventricular end-systolic volume were lower than those of the control group,and the differences were statistically significant(P<0.001);The incidence of adverse reactions in the observation group was lower than that in the control group,and the difference was statistically significant(P=0.039).Conclusion:Xuesaitong has significant effect in treating coronary heart disease.It can optimize blood rheology indicators,promote the recovery of cardiac function and reduce adverse reactions.