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脑内GPS的研究与发现

Research and discovery of "inner GPS" of brain
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摘要 20世纪以来, 随着脑科学研究的进展, 科学家们发现了脑内GPS, 揭示了大脑空间认知的机制。脑内GPS的发现过程经历了3个阶段:1971年, 约翰·奥基夫发现了大脑海马体内的位置细胞, 为脑内GPS研究的开始;1980年, 詹姆斯·兰克发现了大脑内侧内嗅皮层的头部方向细胞, 脑内GPS的研究取得了突破;2005年, 莫泽夫妇发现了网格细胞, 标志着脑内GPS研究的成熟。脑内GPS的发现不仅揭示了大脑在细胞层面的空间认知功能, 还为研究与神经系统相关的疾病提供了理论基础。 Since the 20th century,with the progress of brain science research,scientists have discovered the brain GPS,revealing the mechanism of brain spatial cognition.The discovery process of brain GPS has gone through three stages.In 1971,John O'Keefe discovered the position cells in the hippocampus of the brain,which was the beginning of the research on the GPS in the brain;In 1900,James Rank discovered the head direction cells in the medial entorhinal cortex of the brain,and the research on the GPS in the brain made a breakthrough;In 2005,Edvard I.Moser and his wife discovered grid cells,marking the maturity of the research on GPS in the brain.The discovery of intracerebral GPS not only reveals the spatial cognitive function of the brain at the cellular level,but also provides a theoretical basis for the study of diseases related to the nervous system.
作者 陈甜甜 李志平 Chen Tiantian;Li Zhiping(Department of Medical History,School of Basic Medicine Sciences,Harbin Medical University,Harbin 150076,China)
出处 《中华医史杂志》 2023年第4期251-256,共6页 Chinese Journal of Medical History
关键词 海马体 脑内GPS 位置细胞 网格细胞 Hippocampus "Inner GPS"of Brain Place cell Grid cell
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