脑血疏口服液治疗颅脑外伤继发性脑出血的临床研究

Clinical study of Naoxueshu oral liquid in the treatment of secondary cerebral hemorrhage after craniocerebral trauma

目的:探究脑血疏口服液应用于颅脑外伤继发性脑出血患者的临床效果。方法:选择盐城市大丰人民医院2020年6月—2021年9月间收治的86例颅脑外伤继发性脑出血患者纳入研究,按奇偶数将其均分为对照组和脑血疏治疗组各43例。对照组患者接受脑出血常规治疗,脑血疏治疗组除常规治疗外,于生命体征平稳3 d后每日加服脑血疏口服液。治疗1个月后对比两组的临床疗效,并于患者接受治疗前和接受治疗2、4周时查颅脑CT以确定血肿大小。结果:两组在一段时间的治疗后均取得了明显的效果,血肿体积较住院前明显变小,且脑血疏治疗组的总有效率(95.35%)明显高于对照组(81.40%)。在治疗进行到第2周和第4周时,与对照组相比,脑血疏治疗组的血肿体积都明显缩小,Barthel指数(Barthel index,BI)评分升高,美国国立卫生研究院卒中量表(National Institutes of Health Stroke Scale,NIHSS)评分降低(均P<0.05)。结论:脑血疏口服液可促进患者外伤后脑部血肿的吸收,改善神经功能,提高生活质量。

Objective:To study the clinical effect of Naoxueshu oral liquid on patients with secondary cerebral hemorrhage after craniocerebral trauma.Methods:86 patients with secondary intracerebral hemorrhage admitted to Yancheng Dafeng People′s Hospital from June 2020 to September 2021 were selected to participate in the study,and divided into control group and Naoxueshu treatment group according to odd and even numbers,with 43 cases each.The patients in the control group received coventional treatment for cerebral hemorrhage.Besides the conventional treatment,the Naoxueshu oral liquid was taken daily three days after the vital signs were stable.One month after treatment,the clinical efficacy of the two groups was compared,and the brain CT was examined before and at two and four weeks of treatment.Results:The results of data analysis showed that the two groups achieved obvious therapeutic effect after a period of treatment,the volume of hematoma was significantly smaller than before hospitalization,and the total effective rate of Naoxueshu treatment group(95.35%)was significantly higher than that of the control group(81.40%).In the second and fourth week of treatment,compared with control group,the volume of hematoma in the Naoxueshu treatment group was significantly smaller.The Barthel index(BI)scores increased and the National Institutes of Health Stroke Scale(NIHSS)scores decreased(all P<0.05).Conclusion:Naoxueshu oral liquid can promote the absorption of brain hematoma after trauma,improve neurological function,and improve quality of life.