乳腺癌抗血管生成治疗研究进展

Research progress of anti-angiogenic therapy for breast cancer

乳腺癌已成为全球确诊人数最高的肿瘤,是恶性肿瘤的第二大致死病因.肿瘤血管生成在肿瘤进展和转移方面发挥重要作用,已成为一个潜在治疗靶点.近年来,抗血管生成治疗在乳腺癌治疗中的临床研究数据不断增多,与免疫检查点抑制剂联合应用的临床试验也正在开展.文章主要探讨抗血管生成治疗在乳腺癌中的研究进展.

Breast cancer is the most diagnosed carcinoma and the second most common cause of death from cancer worldwide.Tumor angiogenesis plays an important role in the development and metastasis of tumors and has become a potential therapeutic target.In recent years,the clinical data of anti-angiogenic therapy in the treatment of breast cancer is increasing,and the clinical trials of anti-angiogenic therapy in combination with immune checkpoint inhibitors are being carried out.This review mainly discusses the research progress of anti-angiogenic therapy in breast cancer.