具备高危复发因素肝细胞癌手术联合术后辅助放疗的研究进展

Research progress of surgical operation combined with postoperative adjuvant radiotherapy for hepatocellular carcinoma with high risk factors of recurrence

肝切除术是肝细胞癌患者首选根治性治疗方法,但术后复发率高,生存率低.因此,探索可有效改善肝癌患者术后生存的综合治疗策略,是当前的研究热点.文章就中央型肝癌窄切缘肝切除术,病理证实微血管侵犯,术前存在可切除门静脉癌栓的高危复发因素肝细胞癌手术联合术后辅助放疗的研究进展展开讨论综述,以期为临床治疗提供参考性依据.

Hepatectomy is the preferred radical treatment for patients with hepatocellular carcinoma,but the postoperative recurrence rate is high,and the survival rate is low.Therefore,to explore comprehensive treatment strategies that can effectively improve the survival condition of patients with liver cancer after surgery is the current research hotspot.In this paper,the research progress of surgical operation combined with postoperative adjuvant radiotherapy for hepatocellular carcinoma with high risk factors of recurrence,including narrow margin hepatectomy for centrally located hepatocellular carcinoma,pathologically confirmed microvascular invasion and the existence of resectable portal vein tumor thrombus before surgery was reviewed,to provide reference for clinical treatment.