热敏灸治疗青少年室早性心肌病的临床效果及作用机制研究

Study on the Clinical Effect and Mechanism of Heat-Sensitive Moxibustion in the Treatment of Premature Ventricular Cardiomyopathy in Adolescents

目的 探讨热敏灸治疗青少年室早性心肌病的临床效果及作用机制。方法 60例青少年室早性心肌病患者随机分为两组,对照组给予常规西医治疗,观察组在对照组基础上给予热敏灸治疗,比较两组的心功能指标、心率、室性早搏次数及炎性因子水平。结果 治疗后,观察组的LVEF高于对照组,LVESD、 LVEDD、心率、室性早搏次数均低于对照组(P<0.05)。治疗后,观察组的IL-6、 TNF-α水平均低于对照组(P<0.05)。结论 热敏灸治疗青少年室早性心肌病的效果确切,有助于改善患者的心功能,减少室性早搏次数,其机制可能与热敏灸改善炎性反应有关。

Objective To explore the clinical effect and mechanism of heat-sensitive moxibustion in the treatment of premature ventricular cardiomyopathy in adolescents.Methods 60 adolescent patients with premature ventricular cardiomyopathy were randomly divided into two groups.The control group was treated with conventional western medicine,and the observation group was treated with heat-sensitive moxibustion on the basis of the control group.The cardiac function indicators,heart rate,number of ventricular premature beats and levels of inflammatory factors were compared between the two groups.Results After treatment,the LVEF of the observation group was higher than that of the control group,and the LVESD,LVEDD,heart rate and number of ventricular premature beats were lower than those of the control group(P<0.05).After treatment,the levels of IL-6 and TNF-αof the observation group were lower than those of the control group(P<0.05).Conclusions Heat-sensitive moxibustion in the treatment of premature ventricular cardiomyopathy in adolescents has exact effect,which is helpful to improve the cardiac function of patients and reduce the number of ventricular premature beats.The mechanism may be related to the improvement of inflammatory response by heat-sensitive moxibustion.