米非司酮联合地诺孕素治疗子宫内膜异位症痛经的效果

Effect of Mifepristone Combined with Dinogest in the Treatment of Endometriosis Dysmenorrhea

目的 探讨米非司酮联合地诺孕素治疗子宫内膜异位症(EMT)痛经的效果。方法 80例EMT痛经患者按照入组顺序分为两组各40例。对照组采用米非司酮治疗,观察组采用米非司酮+地诺孕素治疗。比较两组的治疗效果、性激素(E_(2)、P、 FSH、 LH)水平。结果 观察组的总有效率为95.00%,高于对照组的72.50%(P<0.05)。治疗后,观察组的痛经、慢性盆腔痛、性交痛评分均低于对照组,E_(2)、 P、 FSH、 LH水平均低于对照组(P<0.05)。结论 米非司酮联合地诺孕素治疗EMT痛经的效果较好,可缓解患者疼痛症状,抑制性激素的表达。

Objective To explore the effect of mifepristone combined with dinogest in the treatment of endometriosis(EMT)dysmenorrhea.Methods 80 patients with EMT dysmenorrhea were divided into two groups according to the order of enrollment,with 40 cases in each group.The control group was treated with mifepristone,and the observation group was treated with mifepristone+dienogest.The therapeutic effect and levels of sex hormones(E_(2),P,FSH,LH)were compared between the two groups.Results The total effective rate in the observation group was 95.00%,higher than 72.50%in the control group(P<0.05).After treatment,the scores of dysmenorrhea,chronic pelvic pain and dyspareunia in the observation group were lower than those in the control group,and the levels of E_(2),P,FSH and LH were lower than those in the control group(P<0.05).Conclusions Mifepristone combined with dinogest in the treatment of EMT dysmenorrhea has good effect,which can relieve the pain symptoms of patients and inhibit the expression of sex hormones.