基于数据挖掘的《妇人大全良方》治疗产后病用药规律分析

Medication rule of A Complete Collection of Effective Prescriptions for Women in the treatment of postpartum diseases:A study based on data mining

目的:探讨《妇人大全良方》“产后门”中治疗产后病的用药规律。方法:收集《妇人大全良方》“产后门”中的中药处方,对其药物组成进行整理,采用中医传承计算平台V 3.0软件进行数据分析。结果:共整理出中药复方416首,涉及中药364味。使用频次≥20次的中药共24味,包括当归、甘草、肉桂、人参、酒等;四气以温性为主,寒、平次之;五味以甘味为主,苦、辛次之;归经以脾经为主,心、肝经次之;功效以补虚类、清热类、活血化瘀类为主;频次≥30次的药物组合有24组,共形成5个核心类方。结论:《妇人大全良方》“产后门”中治疗产后病的处方具有独特的药物使用规律,健脾养血、温经化瘀是其主要治疗法则,对当今产后病的防治仍具参考价值。

Objective:To investigate the medication rule of the postpartum section of A Complete Collection of Effective Prescriptions for Women in the treatment of postpartum diseases.Methods:Traditional Chinese medicine(TCM)prescriptions were collected from the postpartum section of A Complete Collection of Effective Prescriptions for Women,and the composition of drugs was analyzed.Traditional Chinese Medicine Inheritance Computing System V3.0 was used for data analysis.Results:A total of 416 compound TCM prescriptions were collected,involving 364 TCM drugs.There were 24 drugs with a frequency of use of≥20 times,including Angelica sinensis,Radix Glycyrrhizae,cinnamon,Panax ginseng,and alcohol.Most drugs were warm in nature,followed by those with a cold or neutral nature;most drugs had a sweet taste,followed by those with a bitter or pungent taste;most drugs entered the spleen meridian,followed by those entering the heart or liver meridian.Most drugs had a function of tonifying deficiency,clearing heat,or activating blood and resolving stasis.There were 24 drug combinations with a frequency of≥30 times,and 5 core associated prescriptions were formed.Conclusion:The prescriptions in the postpartum section of A Complete Collection of Effective Prescriptions for Women have a unique medication rule in the treatment of postpartum diseases,with the main treatment principles of strengthening the spleen and nourishing the blood and warming the meridians and resolving stasis,which has a certain value for the prevention and treatment of postpartum diseases in the future.