2002-2018年上海市金山区主要消化系统恶性肿瘤发病和死亡趋势分析

Incidence and Mortality Trends of Major Digestive System Cancers in Jinshan District of Shanghai from 2002 to 2018

[目的]分析2002—2018年上海市金山区主要消化系统恶性肿瘤发病和死亡趋势。[方法]根据上海市肿瘤登记系统收集的2002—2018年金山区主要消化系统恶性肿瘤资料及区公安局提供的人口资料,计算结直肠癌、胃癌、肝癌、胰腺癌的发病和死亡粗率及其标化率(按Segi世界标准人口进行标化)、年度变化百分比(APC)等指标。[结果]2002—2018年,金山区新发结直肠癌、胃癌、肝癌和胰腺癌分别为3833、2708、2530、1488例,同期结直肠癌、胃癌、肝癌和胰腺癌死亡分别为1762、1923、2272、1346例。2002—2018年结直肠癌、胃癌、肝癌和胰腺癌粗发病率的APC分别为6.63%、1.79%、-0.35%、6.48%;进行年龄标化后,结直肠癌和胰腺癌发病率的APC仍大于0(3.00%、2.24%);2002—2018年,结直肠癌和胰腺癌的粗死亡率和标化死亡率均呈上升趋势(APC>0),胃癌和肝癌的则均呈下降趋势(APC<0)。主要消化系统恶性肿瘤发病和死亡风险男性均高于女性,发病率和死亡率随年龄增长而增加。[结论]上海市金山区主要消化系统恶性肿瘤中,结直肠癌和胰腺癌发病率和死亡率呈上升趋势,是重点防控癌种,男性和老年人群是重点防治人群。

[Purpose]To analyze the incidence and mortality of major digestive system cancers in Jinshan District of Shanghai from 2002 to 2018.[Methods]The data of major digestive system cancers were obtained from the Shanghai Cancer Registry and the population data were obtained from the Jinshan District Public Security Bureau.The crude rates and age standardized rates(ASR,standardized by Segi’s world standard population)of incidence and mortality,and the annual percentage change(APC)of colorectal,stomach,liver and pancreatic cancers were calculated.[Results]From 2002 to 2018,a total of 3833,2708,2530,1488 cases of colorectal,stomach,liver and pancreatic cancers were diagnosed and the corresponding numbers of deaths were 1762,1923,2272,1346,respectively in Shanghai Jinshan District.The APCs of crude incidence in colorectal,stomach,liver and pancreatic cancers were 6.63%,1.79%,-0.35%and 6.48%,respectively;while those of ASR were 3.00%,-1.74%,-3.69%and 2.24%,respectively.The APCs of crude mortality in colorectal,stomach,liver and pancreatic cancers were 4.92%,-0.20%,-18.94%and 6.40%,respectively;while those of ASR were 0.40%,-4.30%,-5.73%and 2.02%,respectively.The disease risk in male was higher than that in female,the incidence and mortality increased with age.[Conclusion]The incidence of colorectal and pancreatic cancers shows increasing trends in Shanghai Jinshan District,indicating that these two digestive system cancers should be the priority for prevention and control.