2011-2021年山东省济南市女性乳腺癌死亡趋势分析

Trend of Female Breast Cancer Mortality in Jinan from2011 to 2021

[目的]了解济南市女性居民乳腺癌死亡流行病学特征。[方法]收集2011—2021年济南市女性乳腺癌死亡资料,应用SPSS20.0软件,分城乡计算死亡率、标化死亡率、累积死亡率(0~74岁)、截缩死亡率(35~64岁)、潜在减寿年数等指标,并用年度变化百分比(APC)分析乳腺癌死亡变化趋势,采用2000年中国人口普查标准人口对死亡率等指标进行标化。[结果]2011—2021年济南市女性乳腺癌死亡率平均为9.20/10万,标化死亡率为5.53/10万,平均死亡年龄为60.99岁,累积死亡率为0.59%,截缩死亡率为10.68/10万。城区女性乳腺癌死亡地点、最高级别诊断机构、最高诊断依据依次主要是医疗机构、三级医院、病理诊断,农村分别主要是家中、二级医院、临床+理化。城区女性乳腺癌死亡率和标化死亡率历年来均高于农村。农村女性乳腺癌死亡率以年均2.78%的速度上升,变化趋势有统计学意义(P=0.02)。城区女性乳腺癌平均死亡年龄以年均0.50%的速度上升,变化趋势有统计学意义(P=0.01)。城区女性乳腺癌平均死亡年龄高于农村。女性乳腺癌死亡率30岁后逐渐增加,在55~59岁时出现第1次高峰,在65~69岁年龄组出现相对低谷后再呈上升趋势。济南市60岁以上年龄段女性乳腺癌死亡率以年均1.92%的速度上升,变化趋势有统计学意义(P=0.03)。2011—2021年济南市女性乳腺癌除平均减寿年数为农村高于城区外,其他寿命损失指标如潜在减寿年数、标化潜在减寿年数、减寿率、标化减寿率均为城区高于农村。[结论]农村女性和城乡60岁以上女性是济南市乳腺癌防治重点人群,应倡导健康生活方式,做好早期筛查、早期诊断和早期治疗工作。

[Purpose]To investigate the trend of female breast cancer mortality in Jinan from 2011 to 2021.[Methods]Data of female breast cancer deaths in Jinan from 2011 to 2021 were collected.The crude mortality rate and age-standardized mortality rate(ASMR)by Chinese standard population in 2000,cumulative mortality(0~74 years old),truncated mortality(35~64 years old),potential years of life lost(PYLL)and other indicators in urban and rural areas were calculated with SPSS 20.0 software.The annual percentage change(APC)was used to describe the trend of breast cancer death.[Results]From 2011 to 2021,the crude mortality of female breast cancer in Jinan was 9.20/105 and the ASMR was 5.53/105.The average age of death was 60.99 years old.The cumulative mortality was 0.59%and the truncated mortality was 10.68/105.Both crude mortality rate and ASMR in urban areas were higher than those in rural areas for years.The crude mortality rate of female breast cancer in rural areas increased by 2.78%annually(P=0.02).The average age of female breast cancer death increased by 0.50%annually(P=0.01).The average death age in urban areas was higher than that in rural areas.The mortality of female breast cancer increased after age of 30 years until at age of 55~59,then went down and rose again after 65~69 years of age.The mortality of breast cancer in women over 60 years old increased by 1.92%annually from 2011 to 2021(P=0.03).The potential years of life lost(PYLL),standardized potential years of life lost(SPYLL),potential years of life lost rate(PYLL‰),standardized potential years of life lost rate(SPYLL‰)of female breast cancer were higher in urban areas than those in rural areas,but the average years of life lost(AYLL)in rural areas was higher than that in urban areas.[Conclusion]The women in rural areas and those over 60 years old are the priority groups for prevention and control of female breast cancer in Jinan.Healthy lifestyles should be advocated and early screening,early diagnosis and early treatment should be strengthened.