摘要
As a category of nanomaterials with excellent catalytic efficiency,great substrate specificity,and highrecovery efficiency,nanozymes have attracted increasing attention in various biomedical applications.Currently,numbers of nanozyme-assisted strategies have been well developed for the theranostics ofvarious diseases by taking advantages of their multienzyme-like characteristics,low cost,and highstability.As the most prevalent oral diseases,oral infection poses a global hazard to human health,andcurrent therapeutic options are insufficient to resolve all the clinical issues.Based on their admirableactivity,nanozymes can be frequently employed in the identification and treatment of various oral infectious disorders.Herein,we provide a brief review focused on the classification of nanozymes,analysesof nanozyme-based antibacterial mechanism,research progress in oral bacterial control,and representative studies of nanozyme-assisted oral inflammatory management.Moreover,major challenges andpotential opportunities regarding the use of nanozymes in oral infectious diseases are also highlightedand discussed.This review not only summarizes the recent studies of nanozymes in oral infection butalso promotes the further development of enzyme-mimetic strategies towards various oral diseases.
基金
This work was financially supported by National Natural ScienceFoundation of China(grant Nos.22178140,81901036,22075011,21908005)
Jilin Province Science and Technology DevelopmentPlan Project(grant No.20200201358JC)
Fundamental ResearchFunds for the Central Universities(grant No.BUCT-PT-2021-05)
Bethune Plan of Jilin University(grant No.2022B30)
Chinese Stomatological Association Youth Clinical Research Foundation forOrthodontics(grant No.COSeB2021-06).
