摘要
An iron-catalyzed strategy for the rapid synthesis of indolo[2,3-c]quinolines has been developed.This cascade reaction involving alcohol oxidation,nitro reduction,and oxidative annulation was achieved in a one-pot.The present protocol was started from mono-functionalized indoles and readily available benzylic alcohols/aldehydes,affording a variety of functionalized indolo[2,3-c]quinolines in satisfactory yields.
基金
Financial support from the National Natural Science Foundation of China(Nos.21871226 and 21572194)
the Hunan Provincial Natural Science Foundation of China(No.2020JJ5531)
the Open Fund of Guangdong Provincial Key Laboratory of Luminescence from Molecular Aggregates,Guangzhou 510640,China(South China University of Technology)(No.2019B030301003)
the Undergraduate Investigated Study and Innovated Experiment Plan from Ministry of Education of China and Hunan Province is gratefully acknowledged.
