围绝经期女性睡眠质量与代谢指标的相关性研究

Correlation between sleep quality and metabolic indexes in menopausal women

目的探讨围绝经期女性睡眠质量与代谢指标的相关性。方法回顾性选取2021年5月至2022年8月进行体检的符合标准的健康女性440例为研究对象并对其行匹兹堡睡眠质量问卷(PSQI)调查,以PSQI≥8分作为睡眠质量好坏标准分为睡眠质量好组和睡眠质量差组,收集研究对象的代谢指标,筛选影响围绝经期女性睡眠质量的影响因素。结果睡眠质量好组平均年龄明显低于睡眠质量差组(P<0.05)。不同睡眠质量组中,文化程度、经济收入、职业、绝经状态差异有统计学意义(P<0.05),婚姻状况差异无统计学意义(P>0.05)。睡眠质量差组BMI、TG、TC、LDL、FBG水平显著高于睡眠质量好组(P<0.05);HDL显著低于睡眠质量好组(P<0.05)。以睡眠质量为因变量,年龄、文化程度、经济收入、职业、绝经状态、BMI、TG、TC、LDL、FBG、HDL水平为自变量进行Logistic回归分析后发现,年龄、文化程度、职业是围绝经期女性睡眠质量的主要影响因素(P<0.05);矫正年龄、文化程度、职业等因素,Logistic回归分析结果显示,BMI、LDL、HDL、FBG是影响围绝经期女性睡眠质量的独立危险因素(P<0.05)。结论围绝经期女性睡眠质量受代谢水平影响,为改善睡眠质量提供理论支持。

Objective To explore the correlation between sleep quality and metabolic indicators in menopausal women.Methods A total of 440 healthy women who met the inclusion criteria and underwent physical examination at our hospital from May 2021 to August 2022 were retrospectively recruited.They were surveyed for the Pittsburgh Sleep Quality Questionnaire(PSQI).Classified by the PSQI≥8 points,subjects were divided into good sleep quality group and poor sleep quality group.The metabolic indicators were collected,and the influencing factors for sleep quality of menopausal women were screened.Results The mean age in the good sleep quality was significantly lower than that of the poor sleep quality group(P<0.05).There were significant differences in educational level,economic income,occupation,and menopausal status between groups(P<0.05),but no significant difference was detected in marital status(P>0.05).Body mass index(BMI),triglyceride(TG),total cholesterol(TC),low-density lipoprotein(LDL)and fasting blood glucose(FBG)in the poor sleep quality group were significantly higher than those of the good sleep quality group(P<0.05),and the high-density lipoprotein(HDL)was significantly lower(P<0.05).Taking sleep quality as the dependent variable,and age,education level,economic income,occupation,menopausal status,BMI,TG,TC,LDL,FBG,and HDL levels as independent variables,Logistic regression analysis found that age,education level,and occupation were the main influencing factors for sleep quality in menopausal women(P<0.05).After adjusting for age,education level,occupation and other factors,Logistic regression analysis showed that BMI,LDL,HDL,and FBG were independent risk factors for sleep quality in menopausal women(P<0.05).Conclusion Sleep quality of menopausal women is affected by metabolic level,and our findings provide a theoretical support for improving sleep quality.