加速器时代下的核医学诊疗一体化核素及其应用

Application of theranostic nuclide in the era of accelerator

加速器辐照是放射性核素制备的主要方式之一,近年来随着核医学诊疗一体化的发展对加速器放射性核素的制备提出了新的需求。该文将目前可用加速器制备的诊疗核素及核素对分为3种类型:诊疗一体化的核素、同一元素及不同元素的诊疗核素对,介绍了部分核素及核素对的物理性质和目前的应用现状,分析了目前我国加速器制备的放射性核素在应用中面临的问题,并对加速器生产放射性核素诊疗一体化的应用前景进行展望。

Irradiation based on accelerator is the main method of radionuclide production.In recent years,with the development of theranostics of nuclear medicine,there is a new demand for the preparation of accelerator radionuclides.In this paper,the nuclides and nuclide pairs of theranostics prepared by accelerators are divided into the three categories:nuclides of theranostics,nuclide pairs of theranostics of same element and different elements.The physical properties and current applications of some nuclides and nuclide pairs are introduced.The problems in the application of accelerator radionuclides preparation in China are analyzed,and the application prospect of the integration of accelerator radionuclides diagnosis and treatment is prospected.