膈肌超声评估早产儿呼吸功能的应用价值

Application value of diaphragmatic ultrasound in the evaluation of respiratory function in premature infants

目的 探讨膈肌超声在早产儿呼吸功能评估中的应用价值。方法 选取新生儿科收治的早产儿50例,分为呼吸功能异常组30例和呼吸功能正常组20例,另选同期出生日龄<7 d的正常足月儿30例为对照组,均行超声检查测量两侧膈肌位移(DE)、膈肌厚度,计算膈肌厚度变化率(DTF),比较各组内左侧与右侧及各组间上述参数的差异。结果 各组内左侧与右侧DE、DTF比较差异均无统计学意义。各组间左、右侧DE两两比较差异均有统计学意义(均P<0.05)。对照组与呼吸功能正常组、呼吸功能异常组左、右侧DTF比较差异均有统计学意义(均P<0.05);呼吸功能正常组与呼吸功能异常组左、右侧DTF比较差异均无统计学意义。结论 应用膈肌超声能及早发现早产儿膈肌功能的变化,为临床医师提供早产儿呼吸功能相关的辅助诊断信息,有助于指导临床治疗策略的制订和完善。

Objective To investigate the application value of diaphragmatic ultrasound in the evaluation of respiratory function in premature infants.Methods A total of 50 premature infants in the department of neonatology were selected and divided into the abnormal respiratory function group(n=30)and the normal respiratory function group(n=20).Another 30 normal full-term infants with birth age<7 d in the same period were selected as the control group.The diaphragmatic displacement(DE)and diaphragmatic thickness on both sides were measured by ultrasound,and the diaphragmatic thickness change rate(DTF)was calculated.The differences of the above parameters between the left and right sides in both groups and between groups were compared.Results There were no significant difference between left and right DE and DTF in both groups.There were statistical significance in left and right DE between groups(all P<0.05).There were significant differences in left and right DTF among control group,normal respiratory function group and abnormal respiratory function group(all P<0.05).There were no significant difference in left and right DTF between normal respiratory function group and abnormal respiratory function group.Conclusion Diaphragmatic ultrasound can early detect the changes of diaphragmatic function in premature infants,and provide auxiliary diagnostic information for clinicians related to respiratory function of premature infants,which is helpful to guide the formulation and improvement of clinical treatment strategies.