近年来非药物疗法改善帕金森病抑郁研究进展

Research Progress of Non Drug Therapy in Improving Depression of Parkinson’s Disease

帕金森病抑郁作为帕金森病常见的一种非运动症状,其临床表现会在很大程度上影响患者身体功能及生活质量。目前,帕金森病抑郁仍以药物治疗为主,但长期服药易产生耐药性及药物副作用,治疗效果不佳。以非药物治疗为主进行综述整理发现,针灸、太极拳、音乐疗法、健身气功、重复经颅刺激等均可改善帕金森病抑郁,但在临床研究及基础研究的科学性方面具有差异性,如何做到相辅相成、共同改善帕金森病抑郁仍然是一项艰难的挑战。

Parkinson's disease depression is a common non-motor symptom of Parkinson's disease,and its clinical manifestations will greatly affect the physical function and quality of life of patients.At present,drug therapy is still the main treatment for depression in Parkinson's disease,but long-term drug resistance and drug side effects are easy to occur,and the treatment effect is not good.It was found that acupuncture,tai chi,music therapy,health qigong and repetitive transcranial stimulation can improve depression in Parkinson's disease,but there are differences in the scientific nature of clinical research and basic research.How to complement each other and improve depression in Parkinson's disease is still a difficult challenge.