雷贝拉唑联合莫沙必利治疗老年反流性食管炎的效果研究

Effects of rebeprazole combined with mossorride in elderly patients with reflux esophagitis

目的 探究雷贝拉唑联合莫沙必利治疗老年反流性食管炎患者的效果。方法 选取邵武市立医院2021年1—6月收治的46例老年反流性食管炎患者,电脑随机划分为对照组与观察组各23例,对照组应用雷贝拉唑治疗,观察组应用雷贝拉唑联合莫沙必利治疗,对比2组炎症因子水平、24 h pH值检测结果及临床疗效。结果 治疗后观察组患者炎症因子水平较对照组更加趋近于正常范围值(P<0.05);治疗后观察组患者24 h p H值检测结果显著优于对照组(P<0.05);观察组患者临床治疗总有效率显著高于对照组(P<0.05)。结论 应用雷贝拉唑联合莫沙必利治疗老年反流性食管炎,患者炎症因子水平、24 h pH值检测结果及疗效均显著改善,治疗效果理想。

Objective To explore the effect of rabeprazole combined with mosorpiride in treating elderly patients with reflux esophagitis.Methods 46 elderly patients with reflux esophagitis within the time period of January to June 2021 were selected,and 23 patients were randomly divided to the control group and the observation group.The control group was treated with rebeprazole,and the observation group was treated with rebeprazole and mossorride.The comparative indicators were inflammatory factor level,24 h pH value test results and clinical efficacy.Results The level of inflammatory factors in the observation group was closer to the normal range than the control group(P<0.05).The 24 h pH value of patients in the post-treatment observation group(P<0.05),and the total response rate of the observation group was significantly higher than that of the control group(P<0.05).Conclusion Rebeprazole combined with mosapride was used to treat senile reflux esophagitis.The level of inflammatory factors,24 h pH value and treatment response rate were significantly improved.