冠心病心绞痛合并高血压患者发生心血管不良事件的影响因素

Influencing factors of cardiovascular adverse events in patients with coronary heart disease angina pectoris complicated with hypertension

目的:分析冠心病心绞痛合并高血压患者发生心血管不良事件的影响因素。方法:选取2020年1月至2021年1月濮阳县文留镇卫生院收治的241例冠心病心绞痛合并高血压患者进行前瞻性研究,随访6个月,根据患者是否发生心血管不良事件分为发生组和未发生组,比较两组一般资料,分析冠心病心绞痛合并高血压患者发生心血管不良事件的影响因素。结果:241例冠心病心绞痛合并高血压患者中,120例发生心血管不良事件,发生率为49.79%(120/241);两组性别、体质量指数、舒张压占比比较,差异均无统计学意义(P>0.05);两组年龄、吸烟史、心率、冠心病家族史、C反应蛋白(CRP)、治疗依从性、收缩压(SBP)、心肌肌钙蛋白T(cTnT)、有创干预占比比较,差异均有统计学意义(P<0.05);Logistic回归分析结果显示,年龄≥65岁、有吸烟史、心率>100次/min、CRP>10 mg/L、SBP>150 mmHg、cTnT>0.1μg/L、未行有创干预均为冠心病心绞痛合并高血压患者发生心血管不良事件的危险因素(P<0.05)。结论:年龄≥65岁、有吸烟史、心率>100次/min、CRP>10 mg/L、SBP>150 mmHg、cTnT>0.1μg/L、未行有创干预均为冠心病心绞痛合并高血压患者发生心血管不良事件的危险因素。

Objective:To analyze influencing factors of cardiovascular adverse events in patients with coronary heart disease angina pectoris complicated with hypertension.Methods:A prospective study was conducted on 241 patients with coronary heart disease angina pectoris complicated with hypertension admitted to Wenliu Town Health Center of Puyang county from January 2020 to January 2021.These patients were followed up for 6 months.According to the occurrence of cardiovascular adverse events,these patients were divided into occurrence group and nonoccurrence group.The general data of the two groups were compared.The influencing factors of cardiovascular adverse events in these patients with coronary heart disease angina pectoris complicated with hypertension were analyzed.Results:Among the 241 patients with coronary heart disease angina pectoris complicated with hypertension,120 had cardiovascular adverse events with an incidence of 49.79%(120/241).There were no significant differences in the proportions of gender,body mass index and diastolic blood pressure between the two groups(P>0.05).There were statistically significant differences in the proportions of age,smoking history,heart rate,family history of coronary heart disease,C-reactive protein(CRP),treatment compliance,systolic blood pressure(SBP),cardiac troponin T(cTnT),and invasive intervention between the two groups(P<0.05).The Logistic regression analysis results showed that age≥65 years old,smoking history,heart rate>100 beats/min,CRP>10 mg/L,SBP>150 mmHg,cTnT>0.1μg/L and no invasive intervention were risk factors for cardiovascular adverse events in the patients with coronary heart disease angina pectoris complicated with hypertension(P<0.05).Conclusions:Age≥65 years old,smoking history,heart rate>100 beats/min,CRP>10 mg/L,SBP>150 mmHg,cTnT>0.1μg/L,and no invasive intervention are the risk factors for cardiovascular adverse events in the patients with coronary heart disease angina pectoris complicated with hypertension.