慢性便秘发病机制和非手术治疗进展

Progress of Research on Pathogenesis and Non⁃surgical Treatment of Chronic Constipation

慢性便秘是临床常见的消化系统疾病,其病理生理机制复杂且为多因素,病程反复迁延,不仅影响了患者的躯体和精神心理健康,而且给患者带来巨大经济负担,影响了患者的生命质量。本文主要介绍慢性便秘发病机制,以及非药物治疗、药物治疗、调整生活方式和心理干预等非手术治疗方面的新进展,以期为慢性便秘的临床治疗提供参考。

Chronic constipation is a common gastrointestinal disease and the pathophysiology is complicate and multifactorial.The course of chronic constipation is prolonged and repeated,which influences the physical and mental health,resulting in economic burden,and affecting the quality of life.This review summarized the pathogenesis of chronic constipation,as well as the recent advances in non⁃surgical treatment approaches,including non⁃pharmacological intervention,pharmacological treatment,lifestyle adjustment and psychological intervention,so as to provide a basis for the clinical management of chronic constipation.