医护一体化干预对食管癌术后放疗患者临床症状、睡眠质量和免疫功能的影响

Effect of integrated medical and nursing intervention on clinical symptoms,sleep quality,and immune function of postoperative radiotherapy patients with esophageal cancer

目的探讨医护一体化干预对食管癌术后放疗患者临床症状、睡眠质量和免疫功能的影响。方法依照干预方法的不同将98例食管癌患者分为对照组(n=50)和观察组(n=48),对照组患者给予常规干预,观察组患者给予医护一体化干预。比较两组患者的临床症状改善情况、睡眠质量[阿森斯失眠量表(AIS)]及免疫功能指标[淋巴细胞计数(LYM)、免疫球蛋白A(IgA)、免疫球蛋白G(IgG)、免疫球蛋白M(IgM)]。结果干预后,两组患者吞咽困难、进食、反流、疼痛评分均低于本组干预前,观察组患者吞咽困难、进食、反流、疼痛评分均低于对照组,差异均有统计学意义(P﹤0.05)。干预后,两组患者AIS量表各维度评分及总分均低于本组干预前,观察组患者AIS量表各维度评分及总分均低于对照组,差异均有统计学意义(P﹤0.05)。干预后,对照组患者LYM、IgA、IgG、IgM水平均低于本组干预前和观察组,差异均有统计学意义(P﹤0.05)。结论医护一体化干预可改善食管癌术后放疗患者的临床症状、睡眠质量和免疫功能。

Objective To investigate the effect of integrated medical and nursing intervention on clinical symptoms,sleep quality,and immune function of postoperative radiotherapy patients with esophageal cancer.Method A total of 98 patients with esophageal cancer were divided into control group(n=50)and observation group(n=48)according to different intervention methods.Patients in the control group were given routine intervention,and patients in the observation group were given integrated medical and nursing intervention.The improvement of clinical symptoms,sleep quality[Athens insomnia scale(AIS)],and immune function[lymphocyte count(LYM),immunoglobulin A(IgA),immunoglobulin G(IgG),immunoglobulin M(IgM)]were compared between the two groups.Result After the intervention,the scores of dysphagia,eating,reflux,and pain in the two groups were lower than those before the intervention,and the above scores in the observation group were lower than those in the control group,and the differences were statistically significant(P<0.05).After the intervention,the each dimension of AIS scale scores and total scores of the two groups were lower than those before the intervention,the each dimension of AIS scale scores and total scores of the observation group were lower than those of the control group,and the differences were statistically significant(P<0.05).After the intervention,the levels of LYM,IgA,IgG,and IgM in the control group were lower than those before the intervention and the observation group,and the differences were statistically significant(P<0.05).Conclusion Integrated medical and nursing intervention could improve the clinical symptoms,sleep quality,and immune function of postoperative radiotherapy patients with esophageal cancer.