间歇性节食对肥胖和糖尿病影响的研究进展

Research progress on the effect of intermittent fasting on obesity and diabetes

间歇性禁食(intermittent fasting,IF)是指完全或部分禁食与正常饮食交替进行,这种不同于以往的节食方式已成为最近研究的重点。虽然IF的代谢益处在动物实验中已被广泛认可,但目前的临床试验的结果却喜忧参半,且在2型糖尿病(type 2 diabetes mellitus,T2DM)患者中的临床试验结果较少。本文对IF对糖尿病患者和肥胖人群的影响的研究进展进行综述。

Intermittent fasting(IF)refers to alternate periods of ad libitum eating and complete or partial restriction of calories.IF is different from previous diets and has become the focus of recent research.Although the metabolic benefits of IF have been widely accepted in animal experiments,the results of clinical trials are mixed currently,and fewer clinical trials in patients with type 2 diabetes mellitus(T2DM)have been reported.This article reviews the research progress of the effect of IF on diabetic patients and obese people.