摘要
急性早期前体T淋巴细胞白血病(early T-cell precursor acute lymphoblastic leukemia,ETP-ALL)属于早期非成熟的急性T淋巴细胞白血病(T-cell acute lymphoblastic leukemia,T-ALL),其肿瘤细胞即早期前体T细胞为早期从骨髓迁移至胸腺的胸腺细胞亚群,表达丰富的T系、干细胞和髓系相关的转录物,保留着多能分化潜能,是一种成熟阻滞、分化很差的干细胞白血病[1]。
作者
王莹莹
周世颖
胡月梅
罗浩
翁巍
WANG Yingying;ZHOU Shiying;HU Yuemei;LUO Hao;WENG Wei(Department of Pathophysiology,Shanghai Jiao Tong University School of Medicine,Key Laboratory of Cell Differentiation and Apoptosis,Ministry of Education,Shanghai 200025,China;Department of Blood Transfusion,Tong Ren Hospital,Shanghai Jiao Tong University School of Medicine,Shanghai 200336,China;Department of Pathology,Tong Ren Hospital,Shanghai Jiao Tong University School of Medicine,Shanghai 200336,China;Department of Pathology,School of Basic Medicine,Weifang Medical College,Weifang 261053,Shandong Province,China)
出处
《同济大学学报(医学版)》
2023年第5期773-776,共4页
Journal of Tongji University(Medical Science)
基金
山东省自然科学基金青年基金(ZR2020QH095)。
关键词
早期前体T淋巴细胞白血病
皮肌炎
髓系肉瘤
early T-cell precursor acute lymphoblastic leukemia
dermatomyositis
myeloid sarcoma