辽宁省金秋医院口服降糖药物使用情况分析

Application of antidiabetic drugs in elderly patients in Liaoning Jinqiu Hospital

目的了解辽宁省金秋医院(以下简称“本院”)门诊口服降糖药物的种类在老年患者中使用情况,探讨相关降糖药物在老年患者中单用和联合使用的合理性。方法从本院中联医院信息系统(HIS)中,选取2022年1月至6月门诊处方2052张进行整理分析,明确口服降糖药物的使用情况,与《中国老年2型糖尿病防治临床指南(2022年版)》进行比对,分析降糖药物使用的合理性以及本院口服降糖药物使用结构特点。结果研究样本中女性患者处方624张(占比30.42%),男性患者处方1428张(占比69.57%),患者使用频率最高的前2类降糖药物分别为双胍类(占比49.44%)、α-葡萄糖苷酶抑制剂(占比30.43%)。本院单药使用最多,两种口服降糖药物联合使用次之,三种降糖药物联合使用最少。结论本院老年患者降糖药物使用情况符合《中国老年2型糖尿病防治临床指南(2022年版)》,单药使用最多,主要以双胍类、α-葡萄糖苷酶抑制剂使用为主,药物联合使用以双胍类联合α-葡萄糖苷酶抑制剂两种药物联用最多,三种降糖药物及以上联用较少,降糖药物在本院老年患者中临床用药基本规范合理。

Objective To understand the types of oral hypoglycemic drugs used in outpatient clinics of Liaoning Jinqiu Hospital(hereinafter referred to as"our hospital")in elderly patients,and to explore the rationality of related hypoglycemic drugs used alone or in combination in elderly patients.Methods From the Zhonglian hospital information system(HIS)of our hospital,2052 outpatient prescriptions from January to June 2022 were selected for sorting and analysis,to clarify the use of oral hypoglycemic drugs,and compared with the Clinical Guidelines for the Prevention and Treatment of Type 2 Diabetes in the Elderly in China(2022 Edition),to analyze the rationality of the use of hypoglycemic drugs and the structural characteristics of the use of oral hypoglycemic drugs in our hospital.Results In the study sample,there were 624 prescriptions for female patients(30.42%)and 1428 prescriptions for male patients(69.57%).The top two types of hypoglycemic drugs with the highest frequency of use by patients were biguanides(49.44%)α-glucosidase inhibitors(30.43%).Our hospital uses the most single drugs,followed by the combination of two oral hypoglycemic drugs,and the combination of three hypoglycemic drugs is the least.Conclusion The use of hypoglycemic drugs in elderly patients in our hospital is in line with the Clinical Guidelines for the Prevention and Treatment of Type 2 Diabetes in the Elderly in China(2022 Edition),and single drug use is the largest,mainly biguanidesα-glucosidase inhibitors are mainly used,and the combination of drugs is mainly composed of biguanidesα-glucosidase inhibitors are commonly used in combination with two drugs,while three or more hypoglycemic drugs are rarely used in combination.The clinical use of hypoglycemic drugs in elderly patients in our hospital is standardized and reasonable.