分析全自动血细胞分析仪联合血涂片细胞形态学检测在血常规检验中的应用

Analysis the Application of Automatic Blood Cell Analyzer Combined with Blood Smear Cell Morphology Detection in Blood Routine Examination

目的探析在血常规检验中应用全自动血细胞分析仪、血涂片细胞形态学技术联合检测的临床价值。方法运用简单随机抽样法选取2022年1—12月河北燕达陆道培医院检验科临检微生物室接受血常规检验的90例感染性疾病患者作为研究对象,所选患者在血常规检验时均应用全自动血细胞分析仪、血涂片形态学检测,记录与对比全自动血细胞分析仪、血涂片形态学单一检测与联合检测的常规血细胞阳性检出率、异型淋巴细胞阳性检出率、有核红细胞阳性检出率、中毒颗粒/空泡变性阳性检出率。结果全自动血细胞分析仪联合血涂片细胞形态学对中性粒细胞、嗜酸性细胞、淋巴细胞、嗜碱性细胞、单核细胞阳性检出率高于单一检测,差异有统计学意义(P<0.05)。全自动血细胞分析仪联合血涂片形态学检测对异型淋巴细胞、有核红细胞、中毒颗粒/空泡变性阳性检出率分别为97.78%、91.11%、94.44%,高于全自动血细胞分析仪的68.89%、63.33%、75.56%、血涂片形态学的78.89%、71.11%、78.89%单一检测,组间对比,差异有统计学意义(χ^(2)=26.080、19.812、12.944,P<0.05)。结论应用全自动血细胞分析仪联合血涂片细胞形态学检测开展血常规检验,检测的阳性率显著高于单一检测,可为患者病情的诊断与治疗提供参考依据。

Objective To explore the clinical value of automatic blood cell analyzer combined with blood smear cell morphology in blood routine examination.Methods A total of 90 patients with infectious diseases were selected by simple random sampling from January to December 2022 in the clinical microbiology room of Yanda Ludaopei Hospital,Hebei Province.All the selected patients were tested by automatic blood cell analyzer and blood smear morphology during blood routine examination.The positive rates of conventional blood cells,heterologous lymphocytes,nucleated red cells and toxic particles/vacuolar degeneration were recorded and compared by automatic blood cell analyzer,blood smear morphology single test and combined test.Results The positive detection rates of neutrophil,eosinophile,lymphocyte,basophilic cell and monocyte by automatic blood cell analyzer combined with blood smear cell morphology was higher than that of single detection,and the difference was statistically significant(P<0.05).The positive rates of the automatic blood cell analyzer combined with the morphological test of blood smear were 97.78%,91.11%and 94.44%,respectively,for heterologous lymphocyte,nucleated red cell,toxic particle/vacuolar degeneration,were higher than that those of automatic blood cell analyzer 68.89%,63.33%,75.56%and blood smear morphology 78.89%,71.11%,78.89%,and the difference was statistically significant(χ^(2)=26.080,19.812,12.944,P<0.05).Conclusion The positive rate of blood routine test by automatic blood cell analyzer combined with morphological detection of blood smear is significantly higher than that by single detection,which can provide reference for diagnosis and treatment of patients'disease.