MRI扩散加权成像联合CT对肝癌经导管动脉化疗栓塞术后的疗效评估

Evaluation of the efficacy of MRI diffusion weighted imaging combined with CT in transcatheter arterial embolization of liver cancer

目的探讨MRI扩散加权成像(DWI)联合CT增强检查对肝癌经导管动脉化疗栓塞术(TACE)后的疗效评估。方法选取TACE术后肝癌患者60例(87个病灶),均行MRI-DWI和CT检查,以TACE术为金标准,比较不同检查方法对肿瘤残余病灶诊断准确率及对肿瘤残余病灶诊断灵敏度和特异度情况。结果60例TACE术显示87个病灶中,有肿瘤残存病灶64个,无肿瘤残余病灶23个。MRI检查肿瘤残余病灶准确率为71.26%。增强CT诊断肿瘤残余病灶准确率为62.07%。MRI联合增强CT诊断肿瘤残余病灶准确率为94.25%。MRI联合增强CT诊断肿瘤残余病灶准确率高于MRI和增强CT单独诊断,差异有统计学意义(P<0.05)。MRI联合增强CT诊断肿瘤残余病灶灵敏度和特异度高于MRI和增强CT,差异有统计学意义(P<0.05)。结论MRI和CT均对肝癌TACE术的疗效有评估价值,MRI-DWI联合增强CT能更清楚显示肿瘤残余情况。