Ⅰ~Ⅲ期结直肠癌西医常规治疗后中医干预指南

Guidelines for TCM Intervention After Conventional Western Medicine Treatment for StageⅠ-ⅢColorectal Cancer

结直肠癌是常见的高发病率恶性肿瘤之一,我国近几十年来生活方式、饮食结构和环境的改变与结直肠癌发病率的升高有关。已有大量研究表明,中医药可作为结直肠癌西医常规治疗后的补充和替代治疗。中医医师在Ⅰ~Ⅲ期结直肠癌患者的治疗中积累了大量临床经验,且证明中医药具有独特疗效,但尚缺乏规范和指导中医诊疗的相关临床实践指南。基于此,笔者根据《世界卫生组织指南制定手册》的指南制定流程及《基于证据体的中医药临床证据分级标准》,在法律法规和技术指导文件的框架下,结合近年来国内外相关的临床研究证据进行证据分级和意见推荐,经专家共识研制形成《Ⅰ~Ⅲ期结直肠癌西医常规治疗后中医干预指南》。该指南介绍了结直肠癌中医干预的病因病机、辨证论治等内容,可为从事结直肠癌防治的中医临床医师、中西医结合临床医师提供指导性意见。

Colorectal cancer is one of the common malignant tumors with high morbidity,and changes in lifestyle,dietary structure and environment in China in recent decades have been associated with an increase in the incidence of colorectal cancer.A large number of studies have shown that traditional Chinese medicine(TCM)can be used as a complementary and alternative treatment for colorectal cancer after conventional western medicine treatment.TCM physicians have accumulated a lot of clinical experience in the treatment of patients with stageⅠ-Ⅲcolorectal cancer,and have proved that TCM has unique efficacy,but there is still a lack of relevant clinical practice guidelines to standardize and guide the diagnosis and treatment of TCM.Based on this,according to the guideline development process of the World Health Organization Handbook for Guideline Development and the Clinical Evidence Grading Criteria on TCM Based on Evidence Body,under the framework of relevant laws,regulations and technical guidance documents,combined with the evidence of relevant domestic and foreign clinical research in recent years for evidence grading and opinion recommendation,and then the Guidelines for TCM Intervention After Conventional Western Medicine Treatment for StageⅠ-ⅢColorectal Cancer were developed by expert consensus.This guideline introduces the etiology,pathogenesis,syndrome differentiation and treatment of TCM intervention for colorectal cancer,which can provide guiding opinions for TCM clinicians and clinicians of integrated traditional Chinese and western medicine engaged in the prevention and treatment of colorectal cancer.