探索共同项目负责人模式促进学科交叉融合

Explorating M-PI Model and Promoting Interdisciplinary Integration

共同项目负责人(Multiple-Principal Investigator,M-PI)制度是美国国立卫生研究院(National Institutes of Health,NIH)科研项目的重要特征,目前NIH多种研究类项目已采用M-PI模式。M-PI允许在一个项目中设立多个PI,他们在指导项目完成方面具有同等权力和责任。M-PI项目的评审原则与单一PI项目相同,但需要另外提供一份领导方案,说明选择M-PI模式的理由及不同PI之间合作方案。自2006年实施以来,M-PI项目数量持续增长,有效促进了生物医学领域学科交叉和深度融合,其科学性和合理性已得到广泛认可。国家自然科学基金委员会医学科学部2022年在生命与医学板块专项中试点Co-PI(Co-Principal Investigator)制,有效引导临床与基础学科交叉融合。本文通过分析NIH实施M-PI政策的运行情况和取得的成果,为我国促进学科交叉融合、推动原始创新提供借鉴,为我国科学基金管理制度的改革和完善提供参考。

The multi-PI(M-PI)model is a key feature of NIH research projects,which has been adopted in most NIH research projects.M-PI model allows more than one PI in a project,and all PIs share same responsibility and authority for leading and directing the project.The review criteria of M-PI project were similar to that of single PI project,but a leadership plan should be provided,which described the rationale for choosing M-PI model and the organizational structure of all PIs.Since implementation from 2006,the awarded M-PI projects keep arising,which effectively promoted the interdisciplinary integration in the field of life and medicine,and its scientificity and rationality has been widely recognized.In 2022,the Department of Health Sciences of National Natural Science Foundation of China piloted the Co-PI projects in Life and Medicine,and found it facilitate the integration of clinical and basic medicine.We intend to interpret the implements and achievements of M-PI model,and provide reference for promoting interdisciplinary integration,original innovation,and the reform and improvement of scientific fund management system in China.