通心络胶囊对冠心病稳定型心绞痛患者血脂代谢指标及心功能的影响

Effect of Tongxinluo Capsule on Blood Lipid Metabolism and Cardiac Function in Patients with Stable Angina Pectoris of Coronary Heart Disease

目的探究冠心病稳定型心绞痛患者应用通心络胶囊治疗对血脂代谢指标及心功能的影响。方法按照随机数字表法将我院2020年10月-2022年10月收治的冠心病稳定型心绞痛患者74例分为两组,各37例。对照组服用倍他乐克,观察组加服通心络胶囊。比较两组血脂代谢指标[高密度脂蛋白胆固醇(HDL-C)、胆固醇(TC)、低密度脂蛋白胆固醇(LDL-C)和三酰甘油(TG)]、临床疗效、心功能[左室射血分数(LVEF)、左心室收缩末内径(LVESD)、左心室舒张末期内径(LVEDD)]和不良反应。结果观察组总有效率高于对照组(P<0.05);观察组血脂代谢指标及心功能均优于对照组(P<0.05);两组不良反应发生率对比(P>0.05)。结论冠心病稳定型心绞痛患者采用通心络胶囊治疗,利于提高治疗效果,改善血脂代谢指标和心功能,且不会增加不良反应,安全性较高。

Objective To investigate the effect of Tongxinluo capsule on blood lipid metabolism and cardiac function in patients with stable angina pectoris.Methods 74 patients with stable angina pectoris from October 2020 to October 2022 were randomly divided into two groups,37 in each group.The control group was treated with Betaloc and the observation group was treated with Tongxinluo capsule.The indexes of blood lipid metabolism,such as HDL-C,TC,LDL-C and TG,clinical efficacy,left ventricular ejection fraction(LVEF),left ventricular end-systolic diameter(LVESD)and left ventricular end-diastolic diameter(LVEDD),as well as adverse reactions were compared between the two groups.The patients in the two groups were divided into two groups according to the Low-density lipoprotein.Results The total effective rate in the observation group was higher than that in the control group(P<0.05),the indexes of blood lipid metabolism and cardiac function in the observation group were better than those in the control group(P<0.05),and the incidence of adverse reactions in the two groups was compared(P>0.05).Conclusion Tongxinluo.